Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

Pancreatic cancer remains difficult to treat mainly due to the drug delivery challenges posed by a strong stromal component. Here the authors develop nanocarriers that improve drug delivery efficiency and engage the host immune system against the tumor resulting in reduction of tumor growth and meta...

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Autores principales: Jianqin Lu, Xiangsheng Liu, Yu-Pei Liao, Felix Salazar, Bingbing Sun, Wen Jiang, Chong Hyun Chang, Jinhong Jiang, Xiang Wang, Anna M. Wu, Huan Meng, Andre E. Nel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/5f90acace1374b91a2c015209af90f64
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spelling oai:doaj.org-article:5f90acace1374b91a2c015209af90f642021-12-02T14:42:20ZNano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression10.1038/s41467-017-01651-92041-1723https://doaj.org/article/5f90acace1374b91a2c015209af90f642017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01651-9https://doaj.org/toc/2041-1723Pancreatic cancer remains difficult to treat mainly due to the drug delivery challenges posed by a strong stromal component. Here the authors develop nanocarriers that improve drug delivery efficiency and engage the host immune system against the tumor resulting in reduction of tumor growth and metastasis.Jianqin LuXiangsheng LiuYu-Pei LiaoFelix SalazarBingbing SunWen JiangChong Hyun ChangJinhong JiangXiang WangAnna M. WuHuan MengAndre E. NelNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jianqin Lu
Xiangsheng Liu
Yu-Pei Liao
Felix Salazar
Bingbing Sun
Wen Jiang
Chong Hyun Chang
Jinhong Jiang
Xiang Wang
Anna M. Wu
Huan Meng
Andre E. Nel
Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression
description Pancreatic cancer remains difficult to treat mainly due to the drug delivery challenges posed by a strong stromal component. Here the authors develop nanocarriers that improve drug delivery efficiency and engage the host immune system against the tumor resulting in reduction of tumor growth and metastasis.
format article
author Jianqin Lu
Xiangsheng Liu
Yu-Pei Liao
Felix Salazar
Bingbing Sun
Wen Jiang
Chong Hyun Chang
Jinhong Jiang
Xiang Wang
Anna M. Wu
Huan Meng
Andre E. Nel
author_facet Jianqin Lu
Xiangsheng Liu
Yu-Pei Liao
Felix Salazar
Bingbing Sun
Wen Jiang
Chong Hyun Chang
Jinhong Jiang
Xiang Wang
Anna M. Wu
Huan Meng
Andre E. Nel
author_sort Jianqin Lu
title Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression
title_short Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression
title_full Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression
title_fullStr Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression
title_full_unstemmed Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression
title_sort nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/5f90acace1374b91a2c015209af90f64
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AT jinhongjiang nanoenabledpancreascancerimmunotherapyusingimmunogeniccelldeathandreversingimmunosuppression
AT xiangwang nanoenabledpancreascancerimmunotherapyusingimmunogeniccelldeathandreversingimmunosuppression
AT annamwu nanoenabledpancreascancerimmunotherapyusingimmunogeniccelldeathandreversingimmunosuppression
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AT andreenel nanoenabledpancreascancerimmunotherapyusingimmunogeniccelldeathandreversingimmunosuppression
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