Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli

Gaurav et al. report a synergistic interaction between nalidixic acid and tetracycline against multi-drug resistant bacteria Acinetobacter baumannii and Escherichia coli. They find that this synergy does not work for clinical isolates susceptible to antibiotics, suggesting the potential application...

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Autores principales:	Amit Gaurav, Varsha Gupta, Sandeep K. Shrivastava, Ranjana Pathania
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5fa4ed4a3c9c4db28bbbc07074870b2a
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spelling	oai:doaj.org-article:5fa4ed4a3c9c4db28bbbc07074870b2a2021-12-02T16:57:13ZMechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli10.1038/s42003-021-02074-52399-3642https://doaj.org/article/5fa4ed4a3c9c4db28bbbc07074870b2a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02074-5https://doaj.org/toc/2399-3642Gaurav et al. report a synergistic interaction between nalidixic acid and tetracycline against multi-drug resistant bacteria Acinetobacter baumannii and Escherichia coli. They find that this synergy does not work for clinical isolates susceptible to antibiotics, suggesting the potential application of nalidixic acid and tetracycline against the emergence of multi-drug resistant bacteria.Amit GauravVarsha GuptaSandeep K. ShrivastavaRanjana PathaniaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Amit Gaurav Varsha Gupta Sandeep K. Shrivastava Ranjana Pathania Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
description	Gaurav et al. report a synergistic interaction between nalidixic acid and tetracycline against multi-drug resistant bacteria Acinetobacter baumannii and Escherichia coli. They find that this synergy does not work for clinical isolates susceptible to antibiotics, suggesting the potential application of nalidixic acid and tetracycline against the emergence of multi-drug resistant bacteria.
format	article
author	Amit Gaurav Varsha Gupta Sandeep K. Shrivastava Ranjana Pathania
author_facet	Amit Gaurav Varsha Gupta Sandeep K. Shrivastava Ranjana Pathania
author_sort	Amit Gaurav
title	Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
title_short	Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
title_full	Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
title_fullStr	Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
title_full_unstemmed	Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
title_sort	mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of acinetobacter baumannii and escherichia coli
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5fa4ed4a3c9c4db28bbbc07074870b2a
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Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli

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