Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.

<h4>Background</h4>Prostate cancer is the second most common cancer among men in Uganda, with over 2086 incident cases in 2018. This study's objective was to report the clinical characteristics and primary management of men diagnosed with prostate cancer at the Uganda Cancer Institu...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Paul Katongole, Obondo J Sande, Mulumba Yusuf, Moses Joloba, Steven J Reynolds, Nixon Niyonzima
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5fa73594cf6b4d5f95cd578a60cc9b72
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5fa73594cf6b4d5f95cd578a60cc9b72
record_format	dspace
spelling	oai:doaj.org-article:5fa73594cf6b4d5f95cd578a60cc9b722021-12-02T20:15:51ZClinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.1932-620310.1371/journal.pone.0236458https://doaj.org/article/5fa73594cf6b4d5f95cd578a60cc9b722020-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0236458https://doaj.org/toc/1932-6203<h4>Background</h4>Prostate cancer is the second most common cancer among men in Uganda, with over 2086 incident cases in 2018. This study's objective was to report the clinical characteristics and primary management of men diagnosed with prostate cancer at the Uganda Cancer Institute from 1st January 2015 to 31st December 2019.<h4>Methods</h4>Records from all men diagnosed with Prostate cancer at the Uganda Cancer Institute from 1st January 2015 to 31st December 2019 were reviewed. Clinical characteristics and primary treatment were recorded. Risk categorization was done using the European Society for Medical Oncology prostate cancer risk group classification.<h4>Results</h4>A total of 874 medical records for men diagnosed with prostate cancer was retrieved. The median age was 70 years (interquartile range 64-77). In this study, 501 (57.32%) patients had localized disease. Among patients with localized disease, 2 (0.23%) were classified as low-risk, 5 (0.53%) as intermediate-risk, and 494 (56.52%) as high-risk. Three hundred seventy-three (373) patients had metastatic disease at diagnosis. Among patients with distant metastases, the most common site of metastases was bone 143 (16.36%), followed by spinal cord 54 (6.18%), abdomen 22 (2.52%), and lungs 14 (1.60%). Regarding the primary treatment options majority of the patients were on chemotherapy 384(43.94%) followed by hormonal therapy 336 (38.44%) and radiotherapy 127 (14.53%).<h4>Conclusion</h4>The majority of the patients diagnosed with prostate cancer at the Uganda Cancer Institute presented with advanced disease. The primary treatments were mostly chemotherapy, hormonal therapy, and radiotherapy. There is a need to improve prostate cancer screening in regional health care facilities and the communities to enhance early detection and management of prostate cancer.Paul KatongoleObondo J SandeMulumba YusufMoses JolobaSteven J ReynoldsNixon NiyonzimaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 15, Iss 10, p e0236458 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Paul Katongole Obondo J Sande Mulumba Yusuf Moses Joloba Steven J Reynolds Nixon Niyonzima Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.
description	<h4>Background</h4>Prostate cancer is the second most common cancer among men in Uganda, with over 2086 incident cases in 2018. This study's objective was to report the clinical characteristics and primary management of men diagnosed with prostate cancer at the Uganda Cancer Institute from 1st January 2015 to 31st December 2019.<h4>Methods</h4>Records from all men diagnosed with Prostate cancer at the Uganda Cancer Institute from 1st January 2015 to 31st December 2019 were reviewed. Clinical characteristics and primary treatment were recorded. Risk categorization was done using the European Society for Medical Oncology prostate cancer risk group classification.<h4>Results</h4>A total of 874 medical records for men diagnosed with prostate cancer was retrieved. The median age was 70 years (interquartile range 64-77). In this study, 501 (57.32%) patients had localized disease. Among patients with localized disease, 2 (0.23%) were classified as low-risk, 5 (0.53%) as intermediate-risk, and 494 (56.52%) as high-risk. Three hundred seventy-three (373) patients had metastatic disease at diagnosis. Among patients with distant metastases, the most common site of metastases was bone 143 (16.36%), followed by spinal cord 54 (6.18%), abdomen 22 (2.52%), and lungs 14 (1.60%). Regarding the primary treatment options majority of the patients were on chemotherapy 384(43.94%) followed by hormonal therapy 336 (38.44%) and radiotherapy 127 (14.53%).<h4>Conclusion</h4>The majority of the patients diagnosed with prostate cancer at the Uganda Cancer Institute presented with advanced disease. The primary treatments were mostly chemotherapy, hormonal therapy, and radiotherapy. There is a need to improve prostate cancer screening in regional health care facilities and the communities to enhance early detection and management of prostate cancer.
format	article
author	Paul Katongole Obondo J Sande Mulumba Yusuf Moses Joloba Steven J Reynolds Nixon Niyonzima
author_facet	Paul Katongole Obondo J Sande Mulumba Yusuf Moses Joloba Steven J Reynolds Nixon Niyonzima
author_sort	Paul Katongole
title	Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.
title_short	Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.
title_full	Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.
title_fullStr	Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.
title_full_unstemmed	Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.
title_sort	clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the uganda cancer institute.
publisher	Public Library of Science (PLoS)
publishDate	2020
url	https://doaj.org/article/5fa73594cf6b4d5f95cd578a60cc9b72
work_keys_str_mv	AT paulkatongole clinicalcharacteristicsandprimarymanagementofpatientsdiagnosedwithprostatecancerbetween2015and2019attheugandacancerinstitute AT obondojsande clinicalcharacteristicsandprimarymanagementofpatientsdiagnosedwithprostatecancerbetween2015and2019attheugandacancerinstitute AT mulumbayusuf clinicalcharacteristicsandprimarymanagementofpatientsdiagnosedwithprostatecancerbetween2015and2019attheugandacancerinstitute AT mosesjoloba clinicalcharacteristicsandprimarymanagementofpatientsdiagnosedwithprostatecancerbetween2015and2019attheugandacancerinstitute AT stevenjreynolds clinicalcharacteristicsandprimarymanagementofpatientsdiagnosedwithprostatecancerbetween2015and2019attheugandacancerinstitute AT nixonniyonzima clinicalcharacteristicsandprimarymanagementofpatientsdiagnosedwithprostatecancerbetween2015and2019attheugandacancerinstitute
_version_	1718374527795200000

Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute.

Ejemplares similares