WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

Uda Ho et al find that loss of centriolar scaffold protein WDR62 in mouse testis leads to defects in spermatogenesis. They find that WDR62 deficiency leads to centriole underduplication in spermatocytes and delayed manchette removal in spermatids due to delayed Katanin p80 accumulation.

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Autores principales:	Uda Y. Ho, Chun-Wei Allen Feng, Yvonne Y. Yeap, Amanda L. Bain, Zhe Wei, Belal Shohayeb, Melissa E. Reichelt, Hayden Homer, Kum Kum Khanna, Josephine Bowles, Dominic C. H. Ng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5fa87d30eabf4504b9c5fb5bd757b344
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:5fa87d30eabf4504b9c5fb5bd757b3442021-12-02T15:02:48ZWDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis10.1038/s42003-021-02171-52399-3642https://doaj.org/article/5fa87d30eabf4504b9c5fb5bd757b3442021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02171-5https://doaj.org/toc/2399-3642Uda Ho et al find that loss of centriolar scaffold protein WDR62 in mouse testis leads to defects in spermatogenesis. They find that WDR62 deficiency leads to centriole underduplication in spermatocytes and delayed manchette removal in spermatids due to delayed Katanin p80 accumulation.Uda Y. HoChun-Wei Allen FengYvonne Y. YeapAmanda L. BainZhe WeiBelal ShohayebMelissa E. ReicheltHayden HomerKum Kum KhannaJosephine BowlesDominic C. H. NgNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Uda Y. Ho Chun-Wei Allen Feng Yvonne Y. Yeap Amanda L. Bain Zhe Wei Belal Shohayeb Melissa E. Reichelt Hayden Homer Kum Kum Khanna Josephine Bowles Dominic C. H. Ng WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
description	Uda Ho et al find that loss of centriolar scaffold protein WDR62 in mouse testis leads to defects in spermatogenesis. They find that WDR62 deficiency leads to centriole underduplication in spermatocytes and delayed manchette removal in spermatids due to delayed Katanin p80 accumulation.
format	article
author	Uda Y. Ho Chun-Wei Allen Feng Yvonne Y. Yeap Amanda L. Bain Zhe Wei Belal Shohayeb Melissa E. Reichelt Hayden Homer Kum Kum Khanna Josephine Bowles Dominic C. H. Ng
author_facet	Uda Y. Ho Chun-Wei Allen Feng Yvonne Y. Yeap Amanda L. Bain Zhe Wei Belal Shohayeb Melissa E. Reichelt Hayden Homer Kum Kum Khanna Josephine Bowles Dominic C. H. Ng
author_sort	Uda Y. Ho
title	WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
title_short	WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
title_full	WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
title_fullStr	WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
title_full_unstemmed	WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
title_sort	wdr62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5fa87d30eabf4504b9c5fb5bd757b344
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WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

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