The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms

Calcium-calmodulin-dependent protein kinase II (CaMKII) is well known for its roles in synaptic plasticity. Using a series of molecular replacement experiments, the authors show that the kinase function of CaMKII is required for long-term plasticity and basal AMPA receptor-mediated transmission.

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Autores principales:	Salvatore Incontro, Javier Díaz-Alonso, Jillian Iafrati, Marta Vieira, Cedric S. Asensio, Vikaas S. Sohal, Katherine W. Roche, Kevin J. Bender, Roger A. Nicoll
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5fb48f87db034bfe9e462aad3de3908e
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spelling	oai:doaj.org-article:5fb48f87db034bfe9e462aad3de3908e2021-12-02T14:38:49ZThe CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms10.1038/s41467-018-04439-72041-1723https://doaj.org/article/5fb48f87db034bfe9e462aad3de3908e2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04439-7https://doaj.org/toc/2041-1723Calcium-calmodulin-dependent protein kinase II (CaMKII) is well known for its roles in synaptic plasticity. Using a series of molecular replacement experiments, the authors show that the kinase function of CaMKII is required for long-term plasticity and basal AMPA receptor-mediated transmission.Salvatore IncontroJavier Díaz-AlonsoJillian IafratiMarta VieiraCedric S. AsensioVikaas S. SohalKatherine W. RocheKevin J. BenderRoger A. NicollNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-21 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Salvatore Incontro Javier Díaz-Alonso Jillian Iafrati Marta Vieira Cedric S. Asensio Vikaas S. Sohal Katherine W. Roche Kevin J. Bender Roger A. Nicoll The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
description	Calcium-calmodulin-dependent protein kinase II (CaMKII) is well known for its roles in synaptic plasticity. Using a series of molecular replacement experiments, the authors show that the kinase function of CaMKII is required for long-term plasticity and basal AMPA receptor-mediated transmission.
format	article
author	Salvatore Incontro Javier Díaz-Alonso Jillian Iafrati Marta Vieira Cedric S. Asensio Vikaas S. Sohal Katherine W. Roche Kevin J. Bender Roger A. Nicoll
author_facet	Salvatore Incontro Javier Díaz-Alonso Jillian Iafrati Marta Vieira Cedric S. Asensio Vikaas S. Sohal Katherine W. Roche Kevin J. Bender Roger A. Nicoll
author_sort	Salvatore Incontro
title	The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
title_short	The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
title_full	The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
title_fullStr	The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
title_full_unstemmed	The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
title_sort	camkii/nmda receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5fb48f87db034bfe9e462aad3de3908e
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The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms

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