Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial
Here the authors report the results of randomized, single-blind, placebocontrolled trial on the effects of a asingle subcutaneous dose of Peginterferon Lambda-1a (Lambda) in 120 outpatients with mild to moderate COVID-19, showing that while treatment is well tolerated it does not shorten the duratio...
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Nature Portfolio
2021
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oai:doaj.org-article:5fbb6d030f594c858730d7fccbf367da2021-12-02T13:26:23ZPeginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial10.1038/s41467-021-22177-12041-1723https://doaj.org/article/5fbb6d030f594c858730d7fccbf367da2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22177-1https://doaj.org/toc/2041-1723Here the authors report the results of randomized, single-blind, placebocontrolled trial on the effects of a asingle subcutaneous dose of Peginterferon Lambda-1a (Lambda) in 120 outpatients with mild to moderate COVID-19, showing that while treatment is well tolerated it does not shorten the duration of SARS-CoV-2 viral shedding nor improves symptoms.Prasanna JagannathanJason R. AndrewsHector BonillaHaley HedlinKaren B. JacobsonVidhya BalasubramanianNatasha PuringtonSavita KambleChristiaan R. de VriesOrlando QuinteroKent FengCatherine LeyDean WinslowJennifer NewberryKarlie EdwardsColin HislopIngrid ChoongYvonne MaldonadoJeffrey GlennAmi BhattCatherine BlishTaia WangChaitan KhoslaBenjamin A. PinskyManisha DesaiJulie ParsonnetUpinder SinghNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
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Science Q Prasanna Jagannathan Jason R. Andrews Hector Bonilla Haley Hedlin Karen B. Jacobson Vidhya Balasubramanian Natasha Purington Savita Kamble Christiaan R. de Vries Orlando Quintero Kent Feng Catherine Ley Dean Winslow Jennifer Newberry Karlie Edwards Colin Hislop Ingrid Choong Yvonne Maldonado Jeffrey Glenn Ami Bhatt Catherine Blish Taia Wang Chaitan Khosla Benjamin A. Pinsky Manisha Desai Julie Parsonnet Upinder Singh Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial |
| description |
Here the authors report the results of randomized, single-blind, placebocontrolled trial on the effects of a asingle subcutaneous dose of Peginterferon Lambda-1a (Lambda) in 120 outpatients with mild to moderate COVID-19, showing that while treatment is well tolerated it does not shorten the duration of SARS-CoV-2 viral shedding nor improves symptoms. |
| format |
article |
| author |
Prasanna Jagannathan Jason R. Andrews Hector Bonilla Haley Hedlin Karen B. Jacobson Vidhya Balasubramanian Natasha Purington Savita Kamble Christiaan R. de Vries Orlando Quintero Kent Feng Catherine Ley Dean Winslow Jennifer Newberry Karlie Edwards Colin Hislop Ingrid Choong Yvonne Maldonado Jeffrey Glenn Ami Bhatt Catherine Blish Taia Wang Chaitan Khosla Benjamin A. Pinsky Manisha Desai Julie Parsonnet Upinder Singh |
| author_facet |
Prasanna Jagannathan Jason R. Andrews Hector Bonilla Haley Hedlin Karen B. Jacobson Vidhya Balasubramanian Natasha Purington Savita Kamble Christiaan R. de Vries Orlando Quintero Kent Feng Catherine Ley Dean Winslow Jennifer Newberry Karlie Edwards Colin Hislop Ingrid Choong Yvonne Maldonado Jeffrey Glenn Ami Bhatt Catherine Blish Taia Wang Chaitan Khosla Benjamin A. Pinsky Manisha Desai Julie Parsonnet Upinder Singh |
| author_sort |
Prasanna Jagannathan |
| title |
Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial |
| title_short |
Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial |
| title_full |
Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial |
| title_fullStr |
Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial |
| title_full_unstemmed |
Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial |
| title_sort |
peginterferon lambda-1a for treatment of outpatients with uncomplicated covid-19: a randomized placebo-controlled trial |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/5fbb6d030f594c858730d7fccbf367da |
| work_keys_str_mv |
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