Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes

Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes

Cancer stem cells (CSCs) are known to induce chemotherapy resistance, and cause tumour relapse and metastasis. Here, the authors develop photoactive nanocarbon complexes with second near-infrared photothermal ability to target cancer cells overexpressing the receptor TRPV2 and show it to suppress CS...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yue Yu, Xi Yang, Sheethal Reghu, Sunil C. Kaul, Renu Wadhwa, Eijiro Miyako
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/5fc2eb9e24d74d5283068e31f2322be1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:5fc2eb9e24d74d5283068e31f2322be1
record_format dspace
spelling oai:doaj.org-article:5fc2eb9e24d74d5283068e31f2322be12021-12-02T18:01:15ZPhotothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes10.1038/s41467-020-17768-32041-1723https://doaj.org/article/5fc2eb9e24d74d5283068e31f2322be12020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17768-3https://doaj.org/toc/2041-1723Cancer stem cells (CSCs) are known to induce chemotherapy resistance, and cause tumour relapse and metastasis. Here, the authors develop photoactive nanocarbon complexes with second near-infrared photothermal ability to target cancer cells overexpressing the receptor TRPV2 and show it to suppress CSCs through dysregulation of the Wnt/β-catenin signalling pathway.Yue YuXi YangSheethal ReghuSunil C. KaulRenu WadhwaEijiro MiyakoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yue Yu
Xi Yang
Sheethal Reghu
Sunil C. Kaul
Renu Wadhwa
Eijiro Miyako
Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
description Cancer stem cells (CSCs) are known to induce chemotherapy resistance, and cause tumour relapse and metastasis. Here, the authors develop photoactive nanocarbon complexes with second near-infrared photothermal ability to target cancer cells overexpressing the receptor TRPV2 and show it to suppress CSCs through dysregulation of the Wnt/β-catenin signalling pathway.
format article
author Yue Yu
Xi Yang
Sheethal Reghu
Sunil C. Kaul
Renu Wadhwa
Eijiro Miyako
author_facet Yue Yu
Xi Yang
Sheethal Reghu
Sunil C. Kaul
Renu Wadhwa
Eijiro Miyako
author_sort Yue Yu
title Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
title_short Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
title_full Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
title_fullStr Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
title_full_unstemmed Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
title_sort photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/5fc2eb9e24d74d5283068e31f2322be1
work_keys_str_mv AT yueyu photothermogeneticinhibitionofcancerstemnessbynearinfraredlightactivatablenanocomplexes
AT xiyang photothermogeneticinhibitionofcancerstemnessbynearinfraredlightactivatablenanocomplexes
AT sheethalreghu photothermogeneticinhibitionofcancerstemnessbynearinfraredlightactivatablenanocomplexes
AT sunilckaul photothermogeneticinhibitionofcancerstemnessbynearinfraredlightactivatablenanocomplexes
AT renuwadhwa photothermogeneticinhibitionofcancerstemnessbynearinfraredlightactivatablenanocomplexes
AT eijiromiyako photothermogeneticinhibitionofcancerstemnessbynearinfraredlightactivatablenanocomplexes
_version_ 1718378991766732800

Ejemplares similares