Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells
Trisomy 21 (T21) is a major cause of Down syndrome but little is known about its impact on the cellular proteome. Here, the authors define the proteome of T21 fibroblasts and its turnover and also map proteomic differences in monozygotic T21-discordant twins, revealing extensive, organelle-specific...
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Auteurs principaux: | , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/5fd1464d14644e54b82f2a253ca5d0c7 |
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