Identification of osteogenic progenitor cell-targeted peptides that augment bone formation

Activation of osteogenic cells is essential for bone regeneration. Here, the authors screen a peptide library and identify 2 compounds that promote osteogenic progenitor cell differentiation in vitro, and show that they increase bone formation and fracture repair in mice.

Guardado en:

Detalles Bibliográficos
Autores principales:	Min Jiang, Ruiwu Liu, Lixian Liu, Alexander Kot, Xueping Liu, Wenwu Xiao, Junjing Jia, Yuanpei Li, Kit S. Lam, Wei Yao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5ff53e7e00854267b6246944d4363749
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5ff53e7e00854267b6246944d4363749
record_format	dspace
spelling	oai:doaj.org-article:5ff53e7e00854267b6246944d43637492021-12-02T19:02:25ZIdentification of osteogenic progenitor cell-targeted peptides that augment bone formation10.1038/s41467-020-17417-92041-1723https://doaj.org/article/5ff53e7e00854267b6246944d43637492020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17417-9https://doaj.org/toc/2041-1723Activation of osteogenic cells is essential for bone regeneration. Here, the authors screen a peptide library and identify 2 compounds that promote osteogenic progenitor cell differentiation in vitro, and show that they increase bone formation and fracture repair in mice.Min JiangRuiwu LiuLixian LiuAlexander KotXueping LiuWenwu XiaoJunjing JiaYuanpei LiKit S. LamWei YaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Min Jiang Ruiwu Liu Lixian Liu Alexander Kot Xueping Liu Wenwu Xiao Junjing Jia Yuanpei Li Kit S. Lam Wei Yao Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
description	Activation of osteogenic cells is essential for bone regeneration. Here, the authors screen a peptide library and identify 2 compounds that promote osteogenic progenitor cell differentiation in vitro, and show that they increase bone formation and fracture repair in mice.
format	article
author	Min Jiang Ruiwu Liu Lixian Liu Alexander Kot Xueping Liu Wenwu Xiao Junjing Jia Yuanpei Li Kit S. Lam Wei Yao
author_facet	Min Jiang Ruiwu Liu Lixian Liu Alexander Kot Xueping Liu Wenwu Xiao Junjing Jia Yuanpei Li Kit S. Lam Wei Yao
author_sort	Min Jiang
title	Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
title_short	Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
title_full	Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
title_fullStr	Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
title_full_unstemmed	Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
title_sort	identification of osteogenic progenitor cell-targeted peptides that augment bone formation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5ff53e7e00854267b6246944d4363749
work_keys_str_mv	AT minjiang identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT ruiwuliu identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT lixianliu identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT alexanderkot identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT xuepingliu identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT wenwuxiao identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT junjingjia identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT yuanpeili identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT kitslam identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation AT weiyao identificationofosteogenicprogenitorcelltargetedpeptidesthataugmentboneformation
_version_	1718377267181125632

Identification of osteogenic progenitor cell-targeted peptides that augment bone formation

Ejemplares similares