Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation

The integron integrases have evolved to perform recombination of single and double stranded DNA. Here the authors show that the ancestral pathway is still functional at double stranded sites, revealing the evolution towards the modern resolution pathway.

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Autores principales:	Jose Antonio Escudero, Celine Loot, Vincent Parissi, Aleksandra Nivina, Christiane Bouchier, Didier Mazel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5ff731a853704585826cbd728cd82bf2
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spelling	oai:doaj.org-article:5ff731a853704585826cbd728cd82bf22021-12-02T16:57:49ZUnmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation10.1038/ncomms109372041-1723https://doaj.org/article/5ff731a853704585826cbd728cd82bf22016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10937https://doaj.org/toc/2041-1723The integron integrases have evolved to perform recombination of single and double stranded DNA. Here the authors show that the ancestral pathway is still functional at double stranded sites, revealing the evolution towards the modern resolution pathway.Jose Antonio EscuderoCeline LootVincent ParissiAleksandra NivinaChristiane BouchierDidier MazelNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jose Antonio Escudero Celine Loot Vincent Parissi Aleksandra Nivina Christiane Bouchier Didier Mazel Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
description	The integron integrases have evolved to perform recombination of single and double stranded DNA. Here the authors show that the ancestral pathway is still functional at double stranded sites, revealing the evolution towards the modern resolution pathway.
format	article
author	Jose Antonio Escudero Celine Loot Vincent Parissi Aleksandra Nivina Christiane Bouchier Didier Mazel
author_facet	Jose Antonio Escudero Celine Loot Vincent Parissi Aleksandra Nivina Christiane Bouchier Didier Mazel
author_sort	Jose Antonio Escudero
title	Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
title_short	Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
title_full	Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
title_fullStr	Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
title_full_unstemmed	Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
title_sort	unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/5ff731a853704585826cbd728cd82bf2
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Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation

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