Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation

The integron integrases have evolved to perform recombination of single and double stranded DNA. Here the authors show that the ancestral pathway is still functional at double stranded sites, revealing the evolution towards the modern resolution pathway.

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Bibliographic Details
Main Authors: Jose Antonio Escudero, Celine Loot, Vincent Parissi, Aleksandra Nivina, Christiane Bouchier, Didier Mazel
Format: article
Language:EN
Published: Nature Portfolio 2016
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Q
Online Access:https://doaj.org/article/5ff731a853704585826cbd728cd82bf2
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