Efficacy of Potassium Citrate Solution in Children with Urolithiasis

BACKGROUND AND OBJECTIVE: Diagnosis and treatment of renal stone are very important especially according to non-special symptoms and risk of complication in children. According to invasive surgical methods for treatment of these patients, this study was done to evaluate oral potassium citrate soluti...

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Autores principales:	H Sorkhi, F Hedaiati, A Bijani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2011
Materias:	renal calculi kidney pediatrics potassium citrate Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/5ffa7d79bc274121bc4a1ee54c053fca
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spelling	oai:doaj.org-article:5ffa7d79bc274121bc4a1ee54c053fca2021-11-10T08:56:58ZEfficacy of Potassium Citrate Solution in Children with Urolithiasis1561-41072251-7170https://doaj.org/article/5ffa7d79bc274121bc4a1ee54c053fca2011-11-01T00:00:00Zhttp://jbums.org/article-1-3928-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Diagnosis and treatment of renal stone are very important especially according to non-special symptoms and risk of complication in children. According to invasive surgical methods for treatment of these patients, this study was done to evaluate oral potassium citrate solution efficacy in children with urolithiasis.METHODS: This quasi experimental study was done on 150 children who referred to nephrology department or clinic with renal stone and without urinary obstruction (2002-2010). All children were treated with potassium citrate solution initially 1 ml/kg/day and then it was increased till urine PH reached to above 6.5-7. Urinary ultrasonography was done every 3 months and response to treatment was evaluated according to the stone size, age and duration of treatment.FINDINGS: The age of children was 25 days to 15 years (Mean 36.7±37.4 month). Eighty five cases (56.6%) were male and 65 (43.4%) were female. The rate of complete response to drug (absence of stone) was 78.7% during one year. Mean of follow up was 15.9± 14.6 months and the risk of relapse (recurrence of stone) was 12.4%. There weren’t significant difference between response to treatment and stone size, age and children sex.CONCLUSION: Potassium citrate has been found to be significantly effective in treatment of renal stone, so we suggest using this drug for treatment of renal stone in all children without urinary obstruction.H SorkhiF HedaiatiA BijaniBabol University of Medical Sciencesarticlerenal calculikidneypediatricspotassium citrateMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 13, Iss 6, Pp 73-79 (2011)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	renal calculi kidney pediatrics potassium citrate Medicine R Medicine (General) R5-920
spellingShingle	renal calculi kidney pediatrics potassium citrate Medicine R Medicine (General) R5-920 H Sorkhi F Hedaiati A Bijani Efficacy of Potassium Citrate Solution in Children with Urolithiasis
description	BACKGROUND AND OBJECTIVE: Diagnosis and treatment of renal stone are very important especially according to non-special symptoms and risk of complication in children. According to invasive surgical methods for treatment of these patients, this study was done to evaluate oral potassium citrate solution efficacy in children with urolithiasis.METHODS: This quasi experimental study was done on 150 children who referred to nephrology department or clinic with renal stone and without urinary obstruction (2002-2010). All children were treated with potassium citrate solution initially 1 ml/kg/day and then it was increased till urine PH reached to above 6.5-7. Urinary ultrasonography was done every 3 months and response to treatment was evaluated according to the stone size, age and duration of treatment.FINDINGS: The age of children was 25 days to 15 years (Mean 36.7±37.4 month). Eighty five cases (56.6%) were male and 65 (43.4%) were female. The rate of complete response to drug (absence of stone) was 78.7% during one year. Mean of follow up was 15.9± 14.6 months and the risk of relapse (recurrence of stone) was 12.4%. There weren’t significant difference between response to treatment and stone size, age and children sex.CONCLUSION: Potassium citrate has been found to be significantly effective in treatment of renal stone, so we suggest using this drug for treatment of renal stone in all children without urinary obstruction.
format	article
author	H Sorkhi F Hedaiati A Bijani
author_facet	H Sorkhi F Hedaiati A Bijani
author_sort	H Sorkhi
title	Efficacy of Potassium Citrate Solution in Children with Urolithiasis
title_short	Efficacy of Potassium Citrate Solution in Children with Urolithiasis
title_full	Efficacy of Potassium Citrate Solution in Children with Urolithiasis
title_fullStr	Efficacy of Potassium Citrate Solution in Children with Urolithiasis
title_full_unstemmed	Efficacy of Potassium Citrate Solution in Children with Urolithiasis
title_sort	efficacy of potassium citrate solution in children with urolithiasis
publisher	Babol University of Medical Sciences
publishDate	2011
url	https://doaj.org/article/5ffa7d79bc274121bc4a1ee54c053fca
work_keys_str_mv	AT hsorkhi efficacyofpotassiumcitratesolutioninchildrenwithurolithiasis AT fhedaiati efficacyofpotassiumcitratesolutioninchildrenwithurolithiasis AT abijani efficacyofpotassiumcitratesolutioninchildrenwithurolithiasis
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Efficacy of Potassium Citrate Solution in Children with Urolithiasis

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