Innate Lymphoid Cells and Myocardial Infarction

Myocardial infarction results from obstruction of a coronary artery that causes insufficient blood supply to the myocardium and leads to ischemic necrosis. It is one of the most common diseases threatening human health and is characterized by high morbidity and mortality. Atherosclerosis is the path...

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Autores principales: Wenling Yang, Jibin Lin, Jin Zhou, Yuqi Zheng, Shijiu Jiang, Shaolin He, Dazhu Li
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/6000b2a0d6be47d1af91a33c93180e18
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spelling oai:doaj.org-article:6000b2a0d6be47d1af91a33c93180e182021-11-11T05:30:53ZInnate Lymphoid Cells and Myocardial Infarction1664-322410.3389/fimmu.2021.758272https://doaj.org/article/6000b2a0d6be47d1af91a33c93180e182021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.758272/fullhttps://doaj.org/toc/1664-3224Myocardial infarction results from obstruction of a coronary artery that causes insufficient blood supply to the myocardium and leads to ischemic necrosis. It is one of the most common diseases threatening human health and is characterized by high morbidity and mortality. Atherosclerosis is the pathological basis of myocardial infarction, and its pathogenesis has not been fully elucidated. Innate lymphoid cells (ILCs) are an important part of the human immune system and participate in many processes, including inflammation, metabolism and tissue remodeling, and play an important role in atherosclerosis. However, their specific roles in myocardial infarction are unclear. This review describes the current understanding of the relationship between innate lymphoid cells and myocardial infarction during the acute phase of myocardial infarction, myocardial ischemia-reperfusion injury, and heart repair and regeneration following myocardial infarction. We suggest that this review may provide new potential intervention targets and ideas for treatment and prevention of myocardial infarction.Wenling YangJibin LinJin ZhouYuqi ZhengShijiu JiangShaolin HeDazhu LiFrontiers Media S.A.articlemyocardial infarctioninnate lymphoid cellsmyocardial ischemia-reperfusion injuryregeneration and repair after myocardial infarctionthe acute phase of myocardial infarctionImmunologic diseases. AllergyRC581-607ENFrontiers in Immunology, Vol 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic myocardial infarction
innate lymphoid cells
myocardial ischemia-reperfusion injury
regeneration and repair after myocardial infarction
the acute phase of myocardial infarction
Immunologic diseases. Allergy
RC581-607
spellingShingle myocardial infarction
innate lymphoid cells
myocardial ischemia-reperfusion injury
regeneration and repair after myocardial infarction
the acute phase of myocardial infarction
Immunologic diseases. Allergy
RC581-607
Wenling Yang
Jibin Lin
Jin Zhou
Yuqi Zheng
Shijiu Jiang
Shaolin He
Dazhu Li
Innate Lymphoid Cells and Myocardial Infarction
description Myocardial infarction results from obstruction of a coronary artery that causes insufficient blood supply to the myocardium and leads to ischemic necrosis. It is one of the most common diseases threatening human health and is characterized by high morbidity and mortality. Atherosclerosis is the pathological basis of myocardial infarction, and its pathogenesis has not been fully elucidated. Innate lymphoid cells (ILCs) are an important part of the human immune system and participate in many processes, including inflammation, metabolism and tissue remodeling, and play an important role in atherosclerosis. However, their specific roles in myocardial infarction are unclear. This review describes the current understanding of the relationship between innate lymphoid cells and myocardial infarction during the acute phase of myocardial infarction, myocardial ischemia-reperfusion injury, and heart repair and regeneration following myocardial infarction. We suggest that this review may provide new potential intervention targets and ideas for treatment and prevention of myocardial infarction.
format article
author Wenling Yang
Jibin Lin
Jin Zhou
Yuqi Zheng
Shijiu Jiang
Shaolin He
Dazhu Li
author_facet Wenling Yang
Jibin Lin
Jin Zhou
Yuqi Zheng
Shijiu Jiang
Shaolin He
Dazhu Li
author_sort Wenling Yang
title Innate Lymphoid Cells and Myocardial Infarction
title_short Innate Lymphoid Cells and Myocardial Infarction
title_full Innate Lymphoid Cells and Myocardial Infarction
title_fullStr Innate Lymphoid Cells and Myocardial Infarction
title_full_unstemmed Innate Lymphoid Cells and Myocardial Infarction
title_sort innate lymphoid cells and myocardial infarction
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/6000b2a0d6be47d1af91a33c93180e18
work_keys_str_mv AT wenlingyang innatelymphoidcellsandmyocardialinfarction
AT jibinlin innatelymphoidcellsandmyocardialinfarction
AT jinzhou innatelymphoidcellsandmyocardialinfarction
AT yuqizheng innatelymphoidcellsandmyocardialinfarction
AT shijiujiang innatelymphoidcellsandmyocardialinfarction
AT shaolinhe innatelymphoidcellsandmyocardialinfarction
AT dazhuli innatelymphoidcellsandmyocardialinfarction
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