Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9

Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9

Abstract Microfluidic vortex shedding (µVS) can rapidly deliver mRNA to T cells with high yield and minimal perturbation of the cell state. The mechanistic underpinning of µVS intracellular delivery remains undefined and µVS-Cas9 genome editing requires further studies. Herein, we evaluated a series...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Justin A. Jarrell, Brandon J. Sytsma, Leah H. Wilson, Fong L. Pan, Katherine H. W. J. Lau, Giles T. S. Kirby, Adrian A. Lievano, Ryan S. Pawell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/600c810d0b0d45d6a04aaa482fec0696
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares