Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging

Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic lateral sclerosis (ALS) and in postmortem tissue fro...

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Autores principales: Feng Tian, Wenlong Yang, Daniel A. Mordes, Jin-Yuan Wang, Johnny S. Salameh, Joanie Mok, Jeannie Chew, Aarti Sharma, Ester Leno-Duran, Satomi Suzuki-Uematsu, Naoki Suzuki, Steve S. Han, Fa-Ke Lu, Minbiao Ji, Rosanna Zhang, Yue Liu, Jack Strominger, Neil A. Shneider, Leonard Petrucelli, X. Sunney Xie, Kevin Eggan
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/60127ef2c8cc4a6295abca6013b56613
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spelling oai:doaj.org-article:60127ef2c8cc4a6295abca6013b566132021-12-02T14:39:35ZMonitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging10.1038/ncomms132832041-1723https://doaj.org/article/60127ef2c8cc4a6295abca6013b566132016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13283https://doaj.org/toc/2041-1723Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic lateral sclerosis (ALS) and in postmortem tissue from ALS patients.Feng TianWenlong YangDaniel A. MordesJin-Yuan WangJohnny S. SalamehJoanie MokJeannie ChewAarti SharmaEster Leno-DuranSatomi Suzuki-UematsuNaoki SuzukiSteve S. HanFa-Ke LuMinbiao JiRosanna ZhangYue LiuJack StromingerNeil A. ShneiderLeonard PetrucelliX. Sunney XieKevin EgganNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Feng Tian
Wenlong Yang
Daniel A. Mordes
Jin-Yuan Wang
Johnny S. Salameh
Joanie Mok
Jeannie Chew
Aarti Sharma
Ester Leno-Duran
Satomi Suzuki-Uematsu
Naoki Suzuki
Steve S. Han
Fa-Ke Lu
Minbiao Ji
Rosanna Zhang
Yue Liu
Jack Strominger
Neil A. Shneider
Leonard Petrucelli
X. Sunney Xie
Kevin Eggan
Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
description Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic lateral sclerosis (ALS) and in postmortem tissue from ALS patients.
format article
author Feng Tian
Wenlong Yang
Daniel A. Mordes
Jin-Yuan Wang
Johnny S. Salameh
Joanie Mok
Jeannie Chew
Aarti Sharma
Ester Leno-Duran
Satomi Suzuki-Uematsu
Naoki Suzuki
Steve S. Han
Fa-Ke Lu
Minbiao Ji
Rosanna Zhang
Yue Liu
Jack Strominger
Neil A. Shneider
Leonard Petrucelli
X. Sunney Xie
Kevin Eggan
author_facet Feng Tian
Wenlong Yang
Daniel A. Mordes
Jin-Yuan Wang
Johnny S. Salameh
Joanie Mok
Jeannie Chew
Aarti Sharma
Ester Leno-Duran
Satomi Suzuki-Uematsu
Naoki Suzuki
Steve S. Han
Fa-Ke Lu
Minbiao Ji
Rosanna Zhang
Yue Liu
Jack Strominger
Neil A. Shneider
Leonard Petrucelli
X. Sunney Xie
Kevin Eggan
author_sort Feng Tian
title Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
title_short Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
title_full Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
title_fullStr Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
title_full_unstemmed Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
title_sort monitoring peripheral nerve degeneration in als by label-free stimulated raman scattering imaging
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/60127ef2c8cc4a6295abca6013b56613
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