Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic lateral sclerosis (ALS) and in postmortem tissue fro...
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/60127ef2c8cc4a6295abca6013b56613 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:60127ef2c8cc4a6295abca6013b56613 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:60127ef2c8cc4a6295abca6013b566132021-12-02T14:39:35ZMonitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging10.1038/ncomms132832041-1723https://doaj.org/article/60127ef2c8cc4a6295abca6013b566132016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13283https://doaj.org/toc/2041-1723Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic lateral sclerosis (ALS) and in postmortem tissue from ALS patients.Feng TianWenlong YangDaniel A. MordesJin-Yuan WangJohnny S. SalamehJoanie MokJeannie ChewAarti SharmaEster Leno-DuranSatomi Suzuki-UematsuNaoki SuzukiSteve S. HanFa-Ke LuMinbiao JiRosanna ZhangYue LiuJack StromingerNeil A. ShneiderLeonard PetrucelliX. Sunney XieKevin EgganNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Feng Tian Wenlong Yang Daniel A. Mordes Jin-Yuan Wang Johnny S. Salameh Joanie Mok Jeannie Chew Aarti Sharma Ester Leno-Duran Satomi Suzuki-Uematsu Naoki Suzuki Steve S. Han Fa-Ke Lu Minbiao Ji Rosanna Zhang Yue Liu Jack Strominger Neil A. Shneider Leonard Petrucelli X. Sunney Xie Kevin Eggan Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging |
description |
Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic lateral sclerosis (ALS) and in postmortem tissue from ALS patients. |
format |
article |
author |
Feng Tian Wenlong Yang Daniel A. Mordes Jin-Yuan Wang Johnny S. Salameh Joanie Mok Jeannie Chew Aarti Sharma Ester Leno-Duran Satomi Suzuki-Uematsu Naoki Suzuki Steve S. Han Fa-Ke Lu Minbiao Ji Rosanna Zhang Yue Liu Jack Strominger Neil A. Shneider Leonard Petrucelli X. Sunney Xie Kevin Eggan |
author_facet |
Feng Tian Wenlong Yang Daniel A. Mordes Jin-Yuan Wang Johnny S. Salameh Joanie Mok Jeannie Chew Aarti Sharma Ester Leno-Duran Satomi Suzuki-Uematsu Naoki Suzuki Steve S. Han Fa-Ke Lu Minbiao Ji Rosanna Zhang Yue Liu Jack Strominger Neil A. Shneider Leonard Petrucelli X. Sunney Xie Kevin Eggan |
author_sort |
Feng Tian |
title |
Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging |
title_short |
Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging |
title_full |
Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging |
title_fullStr |
Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging |
title_full_unstemmed |
Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging |
title_sort |
monitoring peripheral nerve degeneration in als by label-free stimulated raman scattering imaging |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/60127ef2c8cc4a6295abca6013b56613 |
work_keys_str_mv |
AT fengtian monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT wenlongyang monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT danielamordes monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT jinyuanwang monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT johnnyssalameh monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT joaniemok monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT jeanniechew monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT aartisharma monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT esterlenoduran monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT satomisuzukiuematsu monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT naokisuzuki monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT steveshan monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT fakelu monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT minbiaoji monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT rosannazhang monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT yueliu monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT jackstrominger monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT neilashneider monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT leonardpetrucelli monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT xsunneyxie monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging AT kevineggan monitoringperipheralnervedegenerationinalsbylabelfreestimulatedramanscatteringimaging |
_version_ |
1718390592365395968 |