Epigenetic and genetic components of height regulation

Adult height has a strong genetic component and is highly heritable. Here the authors whole-genome sequence 8,453 Icelanders and find novel parent-of-origin derived associations in IGF2-H19 and DLK1-MEG3.

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Autores principales: Stefania Benonisdottir, Asmundur Oddsson, Agnar Helgason, Ragnar P. Kristjansson, Gardar Sveinbjornsson, Arna Oskarsdottir, Gudmar Thorleifsson, Olafur B. Davidsson, Gudny A. Arnadottir, Gerald Sulem, Brynjar O. Jensson, Hilma Holm, Kristjan F. Alexandersson, Laufey Tryggvadottir, G. Bragi Walters, Sigurjon A. Gudjonsson, Lucas D. Ward, Jon K. Sigurdsson, Paul D. Iordache, Michael L. Frigge, Thorunn Rafnar, Augustine Kong, Gisli Masson, Hannes Helgason, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Patrick Sulem, Kari Stefansson
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/601995f6997a4f46bd7bff4330856811
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spelling oai:doaj.org-article:601995f6997a4f46bd7bff43308568112021-12-02T17:31:19ZEpigenetic and genetic components of height regulation10.1038/ncomms134902041-1723https://doaj.org/article/601995f6997a4f46bd7bff43308568112016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13490https://doaj.org/toc/2041-1723Adult height has a strong genetic component and is highly heritable. Here the authors whole-genome sequence 8,453 Icelanders and find novel parent-of-origin derived associations in IGF2-H19 and DLK1-MEG3.Stefania BenonisdottirAsmundur OddssonAgnar HelgasonRagnar P. KristjanssonGardar SveinbjornssonArna OskarsdottirGudmar ThorleifssonOlafur B. DavidssonGudny A. ArnadottirGerald SulemBrynjar O. JenssonHilma HolmKristjan F. AlexanderssonLaufey TryggvadottirG. Bragi WaltersSigurjon A. GudjonssonLucas D. WardJon K. SigurdssonPaul D. IordacheMichael L. FriggeThorunn RafnarAugustine KongGisli MassonHannes HelgasonUnnur ThorsteinsdottirDaniel F. GudbjartssonPatrick SulemKari StefanssonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefania Benonisdottir
Asmundur Oddsson
Agnar Helgason
Ragnar P. Kristjansson
Gardar Sveinbjornsson
Arna Oskarsdottir
Gudmar Thorleifsson
Olafur B. Davidsson
Gudny A. Arnadottir
Gerald Sulem
Brynjar O. Jensson
Hilma Holm
Kristjan F. Alexandersson
Laufey Tryggvadottir
G. Bragi Walters
Sigurjon A. Gudjonsson
Lucas D. Ward
Jon K. Sigurdsson
Paul D. Iordache
Michael L. Frigge
Thorunn Rafnar
Augustine Kong
Gisli Masson
Hannes Helgason
Unnur Thorsteinsdottir
Daniel F. Gudbjartsson
Patrick Sulem
Kari Stefansson
Epigenetic and genetic components of height regulation
description Adult height has a strong genetic component and is highly heritable. Here the authors whole-genome sequence 8,453 Icelanders and find novel parent-of-origin derived associations in IGF2-H19 and DLK1-MEG3.
format article
author Stefania Benonisdottir
Asmundur Oddsson
Agnar Helgason
Ragnar P. Kristjansson
Gardar Sveinbjornsson
Arna Oskarsdottir
Gudmar Thorleifsson
Olafur B. Davidsson
Gudny A. Arnadottir
Gerald Sulem
Brynjar O. Jensson
Hilma Holm
Kristjan F. Alexandersson
Laufey Tryggvadottir
G. Bragi Walters
Sigurjon A. Gudjonsson
Lucas D. Ward
Jon K. Sigurdsson
Paul D. Iordache
Michael L. Frigge
Thorunn Rafnar
Augustine Kong
Gisli Masson
Hannes Helgason
Unnur Thorsteinsdottir
Daniel F. Gudbjartsson
Patrick Sulem
Kari Stefansson
author_facet Stefania Benonisdottir
Asmundur Oddsson
Agnar Helgason
Ragnar P. Kristjansson
Gardar Sveinbjornsson
Arna Oskarsdottir
Gudmar Thorleifsson
Olafur B. Davidsson
Gudny A. Arnadottir
Gerald Sulem
Brynjar O. Jensson
Hilma Holm
Kristjan F. Alexandersson
Laufey Tryggvadottir
G. Bragi Walters
Sigurjon A. Gudjonsson
Lucas D. Ward
Jon K. Sigurdsson
Paul D. Iordache
Michael L. Frigge
Thorunn Rafnar
Augustine Kong
Gisli Masson
Hannes Helgason
Unnur Thorsteinsdottir
Daniel F. Gudbjartsson
Patrick Sulem
Kari Stefansson
author_sort Stefania Benonisdottir
title Epigenetic and genetic components of height regulation
title_short Epigenetic and genetic components of height regulation
title_full Epigenetic and genetic components of height regulation
title_fullStr Epigenetic and genetic components of height regulation
title_full_unstemmed Epigenetic and genetic components of height regulation
title_sort epigenetic and genetic components of height regulation
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/601995f6997a4f46bd7bff4330856811
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