A mechanistic account of serotonin’s impact on mood

The cognitive computational mechanisms underlying the antidepressant treatment response of SSRIs is not well understood. Here the authors show that SSRI treatment in healthy subjects for a week manifests as an amplification of the perception of positive outcomes when learning occurs in a positive mo...

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Autores principales:	Jochen Michely, Eran Eldar, Ingrid M. Martin, Raymond J. Dolan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6028d947e39345ea83781d5e54358259
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id	oai:doaj.org-article:6028d947e39345ea83781d5e54358259
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spelling	oai:doaj.org-article:6028d947e39345ea83781d5e543582592021-12-02T14:35:46ZA mechanistic account of serotonin’s impact on mood10.1038/s41467-020-16090-22041-1723https://doaj.org/article/6028d947e39345ea83781d5e543582592020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16090-2https://doaj.org/toc/2041-1723The cognitive computational mechanisms underlying the antidepressant treatment response of SSRIs is not well understood. Here the authors show that SSRI treatment in healthy subjects for a week manifests as an amplification of the perception of positive outcomes when learning occurs in a positive mood setting.Jochen MichelyEran EldarIngrid M. MartinRaymond J. DolanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jochen Michely Eran Eldar Ingrid M. Martin Raymond J. Dolan A mechanistic account of serotonin’s impact on mood
description	The cognitive computational mechanisms underlying the antidepressant treatment response of SSRIs is not well understood. Here the authors show that SSRI treatment in healthy subjects for a week manifests as an amplification of the perception of positive outcomes when learning occurs in a positive mood setting.
format	article
author	Jochen Michely Eran Eldar Ingrid M. Martin Raymond J. Dolan
author_facet	Jochen Michely Eran Eldar Ingrid M. Martin Raymond J. Dolan
author_sort	Jochen Michely
title	A mechanistic account of serotonin’s impact on mood
title_short	A mechanistic account of serotonin’s impact on mood
title_full	A mechanistic account of serotonin’s impact on mood
title_fullStr	A mechanistic account of serotonin’s impact on mood
title_full_unstemmed	A mechanistic account of serotonin’s impact on mood
title_sort	mechanistic account of serotonin’s impact on mood
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6028d947e39345ea83781d5e54358259
work_keys_str_mv	AT jochenmichely amechanisticaccountofserotoninsimpactonmood AT eraneldar amechanisticaccountofserotoninsimpactonmood AT ingridmmartin amechanisticaccountofserotoninsimpactonmood AT raymondjdolan amechanisticaccountofserotoninsimpactonmood AT jochenmichely mechanisticaccountofserotoninsimpactonmood AT eraneldar mechanisticaccountofserotoninsimpactonmood AT ingridmmartin mechanisticaccountofserotoninsimpactonmood AT raymondjdolan mechanisticaccountofserotoninsimpactonmood
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A mechanistic account of serotonin’s impact on mood

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