Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes

Riboswitches recognize and respond to specific metabolites by altering gene expression. Here, the authors developed a high-throughput method (PARCEL) to experimentally identify RNA aptamers across transcriptomes.

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Autores principales: Sidika Tapsin, Miao Sun, Yang Shen, Huibin Zhang, Xin Ni Lim, Teodorus Theo Susanto, Siwy Ling Yang, Gui Sheng Zeng, Jasmine Lee, Alexander Lezhava, Ee Lui Ang, Lian Hui Zhang, Yue Wang, Huimin Zhao, Niranjan Nagarajan, Yue Wan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6037c1ae0517468fba41833c832bbefd
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spelling oai:doaj.org-article:6037c1ae0517468fba41833c832bbefd2021-12-02T17:31:16ZGenome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes10.1038/s41467-018-03675-12041-1723https://doaj.org/article/6037c1ae0517468fba41833c832bbefd2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03675-1https://doaj.org/toc/2041-1723Riboswitches recognize and respond to specific metabolites by altering gene expression. Here, the authors developed a high-throughput method (PARCEL) to experimentally identify RNA aptamers across transcriptomes.Sidika TapsinMiao SunYang ShenHuibin ZhangXin Ni LimTeodorus Theo SusantoSiwy Ling YangGui Sheng ZengJasmine LeeAlexander LezhavaEe Lui AngLian Hui ZhangYue WangHuimin ZhaoNiranjan NagarajanYue WanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sidika Tapsin
Miao Sun
Yang Shen
Huibin Zhang
Xin Ni Lim
Teodorus Theo Susanto
Siwy Ling Yang
Gui Sheng Zeng
Jasmine Lee
Alexander Lezhava
Ee Lui Ang
Lian Hui Zhang
Yue Wang
Huimin Zhao
Niranjan Nagarajan
Yue Wan
Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes
description Riboswitches recognize and respond to specific metabolites by altering gene expression. Here, the authors developed a high-throughput method (PARCEL) to experimentally identify RNA aptamers across transcriptomes.
format article
author Sidika Tapsin
Miao Sun
Yang Shen
Huibin Zhang
Xin Ni Lim
Teodorus Theo Susanto
Siwy Ling Yang
Gui Sheng Zeng
Jasmine Lee
Alexander Lezhava
Ee Lui Ang
Lian Hui Zhang
Yue Wang
Huimin Zhao
Niranjan Nagarajan
Yue Wan
author_facet Sidika Tapsin
Miao Sun
Yang Shen
Huibin Zhang
Xin Ni Lim
Teodorus Theo Susanto
Siwy Ling Yang
Gui Sheng Zeng
Jasmine Lee
Alexander Lezhava
Ee Lui Ang
Lian Hui Zhang
Yue Wang
Huimin Zhao
Niranjan Nagarajan
Yue Wan
author_sort Sidika Tapsin
title Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes
title_short Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes
title_full Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes
title_fullStr Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes
title_full_unstemmed Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes
title_sort genome-wide identification of natural rna aptamers in prokaryotes and eukaryotes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6037c1ae0517468fba41833c832bbefd
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