TRPC5 channels participate in pressure-sensing in aortic baroreceptors

The identity of mechanosensors within aortic baroreceptors that sense fluctuations in blood pressure is unclear. Here, Lau et al.show that a cation channel TRPC5 acts as a transducer of mechanical stimuli in aortic baroreceptor neurons in rodents.

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Autores principales: On-Chai Lau, Bing Shen, Ching-On Wong, Yung-Wui Tjong, Chun-Yin Lo, Hui-Chuan Wang, Yu Huang, Wing-Ho Yung, Yang-Chao Chen, Man-Lung Fung, John Anthony Rudd, Xiaoqiang Yao
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/6043789188ed4256af354756dca532c6
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spelling oai:doaj.org-article:6043789188ed4256af354756dca532c62021-12-02T15:34:11ZTRPC5 channels participate in pressure-sensing in aortic baroreceptors10.1038/ncomms119472041-1723https://doaj.org/article/6043789188ed4256af354756dca532c62016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms11947https://doaj.org/toc/2041-1723The identity of mechanosensors within aortic baroreceptors that sense fluctuations in blood pressure is unclear. Here, Lau et al.show that a cation channel TRPC5 acts as a transducer of mechanical stimuli in aortic baroreceptor neurons in rodents.On-Chai LauBing ShenChing-On WongYung-Wui TjongChun-Yin LoHui-Chuan WangYu HuangWing-Ho YungYang-Chao ChenMan-Lung FungJohn Anthony RuddXiaoqiang YaoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
On-Chai Lau
Bing Shen
Ching-On Wong
Yung-Wui Tjong
Chun-Yin Lo
Hui-Chuan Wang
Yu Huang
Wing-Ho Yung
Yang-Chao Chen
Man-Lung Fung
John Anthony Rudd
Xiaoqiang Yao
TRPC5 channels participate in pressure-sensing in aortic baroreceptors
description The identity of mechanosensors within aortic baroreceptors that sense fluctuations in blood pressure is unclear. Here, Lau et al.show that a cation channel TRPC5 acts as a transducer of mechanical stimuli in aortic baroreceptor neurons in rodents.
format article
author On-Chai Lau
Bing Shen
Ching-On Wong
Yung-Wui Tjong
Chun-Yin Lo
Hui-Chuan Wang
Yu Huang
Wing-Ho Yung
Yang-Chao Chen
Man-Lung Fung
John Anthony Rudd
Xiaoqiang Yao
author_facet On-Chai Lau
Bing Shen
Ching-On Wong
Yung-Wui Tjong
Chun-Yin Lo
Hui-Chuan Wang
Yu Huang
Wing-Ho Yung
Yang-Chao Chen
Man-Lung Fung
John Anthony Rudd
Xiaoqiang Yao
author_sort On-Chai Lau
title TRPC5 channels participate in pressure-sensing in aortic baroreceptors
title_short TRPC5 channels participate in pressure-sensing in aortic baroreceptors
title_full TRPC5 channels participate in pressure-sensing in aortic baroreceptors
title_fullStr TRPC5 channels participate in pressure-sensing in aortic baroreceptors
title_full_unstemmed TRPC5 channels participate in pressure-sensing in aortic baroreceptors
title_sort trpc5 channels participate in pressure-sensing in aortic baroreceptors
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/6043789188ed4256af354756dca532c6
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