TRPC5 channels participate in pressure-sensing in aortic baroreceptors
The identity of mechanosensors within aortic baroreceptors that sense fluctuations in blood pressure is unclear. Here, Lau et al.show that a cation channel TRPC5 acts as a transducer of mechanical stimuli in aortic baroreceptor neurons in rodents.
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Nature Portfolio
2016
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oai:doaj.org-article:6043789188ed4256af354756dca532c62021-12-02T15:34:11ZTRPC5 channels participate in pressure-sensing in aortic baroreceptors10.1038/ncomms119472041-1723https://doaj.org/article/6043789188ed4256af354756dca532c62016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms11947https://doaj.org/toc/2041-1723The identity of mechanosensors within aortic baroreceptors that sense fluctuations in blood pressure is unclear. Here, Lau et al.show that a cation channel TRPC5 acts as a transducer of mechanical stimuli in aortic baroreceptor neurons in rodents.On-Chai LauBing ShenChing-On WongYung-Wui TjongChun-Yin LoHui-Chuan WangYu HuangWing-Ho YungYang-Chao ChenMan-Lung FungJohn Anthony RuddXiaoqiang YaoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q On-Chai Lau Bing Shen Ching-On Wong Yung-Wui Tjong Chun-Yin Lo Hui-Chuan Wang Yu Huang Wing-Ho Yung Yang-Chao Chen Man-Lung Fung John Anthony Rudd Xiaoqiang Yao TRPC5 channels participate in pressure-sensing in aortic baroreceptors |
description |
The identity of mechanosensors within aortic baroreceptors that sense fluctuations in blood pressure is unclear. Here, Lau et al.show that a cation channel TRPC5 acts as a transducer of mechanical stimuli in aortic baroreceptor neurons in rodents. |
format |
article |
author |
On-Chai Lau Bing Shen Ching-On Wong Yung-Wui Tjong Chun-Yin Lo Hui-Chuan Wang Yu Huang Wing-Ho Yung Yang-Chao Chen Man-Lung Fung John Anthony Rudd Xiaoqiang Yao |
author_facet |
On-Chai Lau Bing Shen Ching-On Wong Yung-Wui Tjong Chun-Yin Lo Hui-Chuan Wang Yu Huang Wing-Ho Yung Yang-Chao Chen Man-Lung Fung John Anthony Rudd Xiaoqiang Yao |
author_sort |
On-Chai Lau |
title |
TRPC5 channels participate in pressure-sensing in aortic baroreceptors |
title_short |
TRPC5 channels participate in pressure-sensing in aortic baroreceptors |
title_full |
TRPC5 channels participate in pressure-sensing in aortic baroreceptors |
title_fullStr |
TRPC5 channels participate in pressure-sensing in aortic baroreceptors |
title_full_unstemmed |
TRPC5 channels participate in pressure-sensing in aortic baroreceptors |
title_sort |
trpc5 channels participate in pressure-sensing in aortic baroreceptors |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/6043789188ed4256af354756dca532c6 |
work_keys_str_mv |
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1718386901692448768 |