Blind predictions of DNA and RNA tweezers experiments with force and torque.

Single-molecule tweezers measurements of double-stranded nucleic acids (dsDNA and dsRNA) provide unprecedented opportunities to dissect how these fundamental molecules respond to forces and torques analogous to those applied by topoisomerases, viral capsids, and other biological partners. However, t...

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Autores principales: Fang-Chieh Chou, Jan Lipfert, Rhiju Das
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/604e0c15c56442fda588db878df5057e
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