Time-domain based evaluation of detection efficiency in liquid scintillation counting

Abstract This work explores the distribution of time intervals between signals from the photomultiplier tubes (PMTs) of a liquid scintillation counting (LSC) system when a scintillation burst caused by an ionizing particle is detected. This distribution is termed the cross-correlation distribution a...

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Autores principales:	Krasimir Mitev, Chavdar Dutsov, Philippe Cassette, Benoît Sabot
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/604ed554941e492e90efd27106f44250
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spelling	oai:doaj.org-article:604ed554941e492e90efd27106f442502021-12-02T17:40:01ZTime-domain based evaluation of detection efficiency in liquid scintillation counting10.1038/s41598-021-91873-12045-2322https://doaj.org/article/604ed554941e492e90efd27106f442502021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91873-1https://doaj.org/toc/2045-2322Abstract This work explores the distribution of time intervals between signals from the photomultiplier tubes (PMTs) of a liquid scintillation counting (LSC) system when a scintillation burst caused by an ionizing particle is detected. This distribution is termed the cross-correlation distribution and it is shown that it contains information about the probability to detect a scintillation event. A theoretical model that describes the cross-correlation distribution is derived. The model can be used to estimate the mean number of detected photons in a LSC measurement, which allows the calculation of the detection efficiency. The theoretical findings are validated by Monte Carlo simulations and by experiments with low-energy beta-emitting and electron-capture radionuclides ( $$^3\hbox {H}$$ 3 H , $$^{14}\hbox {C}$$ 14 C , $$^{63}\hbox {Ni}$$ 63 Ni and $$^{55}\hbox {Fe}$$ 55 Fe ), with dedicated LSC systems and several commercial LSC cocktails. The results show that some of the parameters of the cross-correlation distribution such as the peak height or the kurtosis can be used as detection efficiency estimators or quenching indicators in LSC. Thus, although the time domain and the cross-correlation distribution have received little to no attention in the practice of LSC, they have the capacity to bring significant improvements in almost all LSC applications related to activity determination of low-energy beta-emitting and electron-capture radionuclides. The results also suggest concepts for the development of innovative LSC systems.Krasimir MitevChavdar DutsovPhilippe CassetteBenoît SabotNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Krasimir Mitev Chavdar Dutsov Philippe Cassette Benoît Sabot Time-domain based evaluation of detection efficiency in liquid scintillation counting
description	Abstract This work explores the distribution of time intervals between signals from the photomultiplier tubes (PMTs) of a liquid scintillation counting (LSC) system when a scintillation burst caused by an ionizing particle is detected. This distribution is termed the cross-correlation distribution and it is shown that it contains information about the probability to detect a scintillation event. A theoretical model that describes the cross-correlation distribution is derived. The model can be used to estimate the mean number of detected photons in a LSC measurement, which allows the calculation of the detection efficiency. The theoretical findings are validated by Monte Carlo simulations and by experiments with low-energy beta-emitting and electron-capture radionuclides ( $$^3\hbox {H}$$ 3 H , $$^{14}\hbox {C}$$ 14 C , $$^{63}\hbox {Ni}$$ 63 Ni and $$^{55}\hbox {Fe}$$ 55 Fe ), with dedicated LSC systems and several commercial LSC cocktails. The results show that some of the parameters of the cross-correlation distribution such as the peak height or the kurtosis can be used as detection efficiency estimators or quenching indicators in LSC. Thus, although the time domain and the cross-correlation distribution have received little to no attention in the practice of LSC, they have the capacity to bring significant improvements in almost all LSC applications related to activity determination of low-energy beta-emitting and electron-capture radionuclides. The results also suggest concepts for the development of innovative LSC systems.
format	article
author	Krasimir Mitev Chavdar Dutsov Philippe Cassette Benoît Sabot
author_facet	Krasimir Mitev Chavdar Dutsov Philippe Cassette Benoît Sabot
author_sort	Krasimir Mitev
title	Time-domain based evaluation of detection efficiency in liquid scintillation counting
title_short	Time-domain based evaluation of detection efficiency in liquid scintillation counting
title_full	Time-domain based evaluation of detection efficiency in liquid scintillation counting
title_fullStr	Time-domain based evaluation of detection efficiency in liquid scintillation counting
title_full_unstemmed	Time-domain based evaluation of detection efficiency in liquid scintillation counting
title_sort	time-domain based evaluation of detection efficiency in liquid scintillation counting
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/604ed554941e492e90efd27106f44250
work_keys_str_mv	AT krasimirmitev timedomainbasedevaluationofdetectionefficiencyinliquidscintillationcounting AT chavdardutsov timedomainbasedevaluationofdetectionefficiencyinliquidscintillationcounting AT philippecassette timedomainbasedevaluationofdetectionefficiencyinliquidscintillationcounting AT benoitsabot timedomainbasedevaluationofdetectionefficiencyinliquidscintillationcounting
_version_	1718379766026862592

Time-domain based evaluation of detection efficiency in liquid scintillation counting

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