Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

In multiple myeloma, malignant cells expand within bone marrow. Here, the authors use multi-region sequencing in patient samples to analyse spatial clonal architecture and heterogeneity, providing novel insight into multiple myeloma progression and evolution.

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Auteurs principaux: L. Rasche, S. S. Chavan, O. W. Stephens, P. H. Patel, R. Tytarenko, C. Ashby, M. Bauer, C. Stein, S. Deshpande, C. Wardell, T. Buzder, G. Molnar, M. Zangari, F. van Rhee, S. Thanendrarajan, C. Schinke, J. Epstein, F. E. Davies, B. A. Walker, T. Meissner, B. Barlogie, G. J. Morgan, N. Weinhold
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Science
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Accès en ligne:https://doaj.org/article/606531925289417ab3689547176c20ed
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https://doaj.org/article/606531925289417ab3689547176c20ed

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