Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories

Memories linking environmental cues to alcohol reward are involved in the development and maintenance of heavy drinking. Here, the authors show that a single dose of ketamine, given after retrieval of alcohol-reward memories, disrupts the reconsolidation of these memories and reduces drinking in hum...

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Autores principales:	Ravi K. Das, Grace Gale, Katie Walsh, Vanessa E. Hennessy, Georges Iskandar, Luke A. Mordecai, Brigitta Brandner, Merel Kindt, H. Valerie Curran, Sunjeev K. Kamboj
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/606a0f7b9edd4aabbf1cf2a46ff7ac24
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spelling	oai:doaj.org-article:606a0f7b9edd4aabbf1cf2a46ff7ac242021-12-02T15:35:35ZKetamine can reduce harmful drinking by pharmacologically rewriting drinking memories10.1038/s41467-019-13162-w2041-1723https://doaj.org/article/606a0f7b9edd4aabbf1cf2a46ff7ac242019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13162-whttps://doaj.org/toc/2041-1723Memories linking environmental cues to alcohol reward are involved in the development and maintenance of heavy drinking. Here, the authors show that a single dose of ketamine, given after retrieval of alcohol-reward memories, disrupts the reconsolidation of these memories and reduces drinking in humans.Ravi K. DasGrace GaleKatie WalshVanessa E. HennessyGeorges IskandarLuke A. MordecaiBrigitta BrandnerMerel KindtH. Valerie CurranSunjeev K. KambojNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ravi K. Das Grace Gale Katie Walsh Vanessa E. Hennessy Georges Iskandar Luke A. Mordecai Brigitta Brandner Merel Kindt H. Valerie Curran Sunjeev K. Kamboj Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
description	Memories linking environmental cues to alcohol reward are involved in the development and maintenance of heavy drinking. Here, the authors show that a single dose of ketamine, given after retrieval of alcohol-reward memories, disrupts the reconsolidation of these memories and reduces drinking in humans.
format	article
author	Ravi K. Das Grace Gale Katie Walsh Vanessa E. Hennessy Georges Iskandar Luke A. Mordecai Brigitta Brandner Merel Kindt H. Valerie Curran Sunjeev K. Kamboj
author_facet	Ravi K. Das Grace Gale Katie Walsh Vanessa E. Hennessy Georges Iskandar Luke A. Mordecai Brigitta Brandner Merel Kindt H. Valerie Curran Sunjeev K. Kamboj
author_sort	Ravi K. Das
title	Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
title_short	Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
title_full	Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
title_fullStr	Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
title_full_unstemmed	Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
title_sort	ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/606a0f7b9edd4aabbf1cf2a46ff7ac24
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Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories

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