Network neighbors of drug targets contribute to drug side-effect similarity.

In pharmacology, it is essential to identify the molecular mechanisms of drug action in order to understand adverse side effects. These adverse side effects have been used to infer whether two drugs share a target protein. However, side-effect similarity of drugs could also be caused by their target...

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Bibliographic Details
Main Authors: Lucas Brouwers, Murat Iskar, Georg Zeller, Vera van Noort, Peer Bork
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/606aaf2812694a1fbfa39c3ac67814eb
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