Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis

Abstract This study aimed to clarify the association between the retinal leakage site on fluorescein angiography (FA) and subfoveal choroidal thickness (SCT) measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Twenty-two patients with Behçet’s uveitis were retrospectively s...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shintaro Shirahama, Toshikatsu Kaburaki, Hisae Nakahara, Rie Tanaka, Keiko Komae, Yujiro Fujino, Hidetoshi Kawashima, Makoto Aihara
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/606be3218d32410294500b1fa68da353
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:606be3218d32410294500b1fa68da353
record_format	dspace
spelling	oai:doaj.org-article:606be3218d32410294500b1fa68da3532021-12-02T15:09:16ZAssociation between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis10.1038/s41598-019-45149-42045-2322https://doaj.org/article/606be3218d32410294500b1fa68da3532019-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-45149-4https://doaj.org/toc/2045-2322Abstract This study aimed to clarify the association between the retinal leakage site on fluorescein angiography (FA) and subfoveal choroidal thickness (SCT) measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Twenty-two patients with Behçet’s uveitis were retrospectively selected in this study. They underwent EDI-OCT and FA in both the active and convalescent phases. The associations of the changes between the active and convalescent phases in SCT and in FA leakage in various retinal areas (total retina, peripheral retina, macula, and optic disc) were examined. The changing rates of SCT between the two investigated phases were significantly associated with the changes in total FA leakage scores (y = 1.79X+ 11.7, r2 = 0.210, p < 0.05). Furthermore, the changes in FA leakage scores in the macula were correlated with the changing rates in SCT (y = 3.72X+ 13.9, r2 = 0.219, p < 0.05). By contrast, there were no significant associations between the changes in SCT and those in leakage from the peripheral retina or the optic disc on FA. These findings demonstrate that SCT may reflect macular vasculitis as determined using FA, and SCT measurement could be a non-invasive method to investigate inflammation near the macula in Behçet’s uveitis.Shintaro ShirahamaToshikatsu KaburakiHisae NakaharaRie TanakaKeiko KomaeYujiro FujinoHidetoshi KawashimaMakoto AiharaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shintaro Shirahama Toshikatsu Kaburaki Hisae Nakahara Rie Tanaka Keiko Komae Yujiro Fujino Hidetoshi Kawashima Makoto Aihara Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis
description	Abstract This study aimed to clarify the association between the retinal leakage site on fluorescein angiography (FA) and subfoveal choroidal thickness (SCT) measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Twenty-two patients with Behçet’s uveitis were retrospectively selected in this study. They underwent EDI-OCT and FA in both the active and convalescent phases. The associations of the changes between the active and convalescent phases in SCT and in FA leakage in various retinal areas (total retina, peripheral retina, macula, and optic disc) were examined. The changing rates of SCT between the two investigated phases were significantly associated with the changes in total FA leakage scores (y = 1.79X+ 11.7, r2 = 0.210, p < 0.05). Furthermore, the changes in FA leakage scores in the macula were correlated with the changing rates in SCT (y = 3.72X+ 13.9, r2 = 0.219, p < 0.05). By contrast, there were no significant associations between the changes in SCT and those in leakage from the peripheral retina or the optic disc on FA. These findings demonstrate that SCT may reflect macular vasculitis as determined using FA, and SCT measurement could be a non-invasive method to investigate inflammation near the macula in Behçet’s uveitis.
format	article
author	Shintaro Shirahama Toshikatsu Kaburaki Hisae Nakahara Rie Tanaka Keiko Komae Yujiro Fujino Hidetoshi Kawashima Makoto Aihara
author_facet	Shintaro Shirahama Toshikatsu Kaburaki Hisae Nakahara Rie Tanaka Keiko Komae Yujiro Fujino Hidetoshi Kawashima Makoto Aihara
author_sort	Shintaro Shirahama
title	Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis
title_short	Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis
title_full	Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis
title_fullStr	Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis
title_full_unstemmed	Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis
title_sort	association between subfoveal choroidal thickness and leakage site on fluorescein angiography in behçet’s uveitis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/606be3218d32410294500b1fa68da353
work_keys_str_mv	AT shintaroshirahama associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis AT toshikatsukaburaki associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis AT hisaenakahara associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis AT rietanaka associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis AT keikokomae associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis AT yujirofujino associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis AT hidetoshikawashima associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis AT makotoaihara associationbetweensubfovealchoroidalthicknessandleakagesiteonfluoresceinangiographyinbehcetsuveitis
_version_	1718387876281974784

Association between subfoveal choroidal thickness and leakage site on fluorescein angiography in Behçet’s uveitis

Ejemplares similares