The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2

Background: Exposure to hydrogen peroxide (H2O2) in addition to increase in the oxidative stress can alter mitochondrial function. The present study aimed to investigate the effect of training with coriander seed consumption on mitochondrial function and oxidative stress markers in the lung tissue o...

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Autores principales:	Zahra Mardani, Seyed Ali Hosseini, Hassan Matinhomaee, Saleh Rahmati-Ahmadabad
Formato:	article
Lenguaje:	EN
Publicado:	Shiraz University of Medical Sciences 2021
Materias:	training coriander oxidative stress lung h2o2 Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/60794bfc1d2e4774af1cedf78e7cc408
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spelling	oai:doaj.org-article:60794bfc1d2e4774af1cedf78e7cc4082021-11-04T07:40:11ZThe Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O22538-18732538-282910.30476/ijns.2021.91492.1139https://doaj.org/article/60794bfc1d2e4774af1cedf78e7cc4082021-09-01T00:00:00Zhttps://ijns.sums.ac.ir/article_47829_c130537a0e379168d520089e3153a9c4.pdfhttps://doaj.org/toc/2538-1873https://doaj.org/toc/2538-2829Background: Exposure to hydrogen peroxide (H2O2) in addition to increase in the oxidative stress can alter mitochondrial function. The present study aimed to investigate the effect of training with coriander seed consumption on mitochondrial function and oxidative stress markers in the lung tissue of rats exposed to H2O2.Methods: Thirty-five rats were divided into 7 groups, including (i) saline healthy control, (ii) saline toxic control, (iii) coriander toxic control (500 mg/kg), (iv) coriander toxic control (1000 mg/kg), (v) coriander toxic training (500 mg/kg), (vi) coriander toxic training (1000 mg/kg), and (vii) saline toxic training groups. During eight weeks, groups 2-7 received 1 mmol/kg H2O2 for three times per week and groups 5-7 performed training three sessions per week.Results: Training and coriander significantly increased adenosine triphosphate (ATP) and decreased caspase-3, cytochrome-C, O-6- methylguanine-DNA methyltransferase (MGMT) and prealbumin (PAB) (p≤0.05). Also, interactive effects of training and coriander on increase of ATP and decrease of caspase-3, cytochrome-C, and PAB at a dose of 1000 mg/kg were higher than 500 mg/kg (p≤0.05).Conclusion: Although training and coriander alone could enhance the mitochondrial function and oxidative stress markers, training simultaneously with coriander had more favorable effects compared to each one alone.Zahra MardaniSeyed Ali HosseiniHassan MatinhomaeeSaleh Rahmati-AhmadabadShiraz University of Medical Sciencesarticletrainingcorianderoxidative stresslungh2o2Nutritional diseases. Deficiency diseasesRC620-627ENInternational Journal of Nutrition Sciences, Vol 6, Iss 3, Pp 141-147 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	training coriander oxidative stress lung h2o2 Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	training coriander oxidative stress lung h2o2 Nutritional diseases. Deficiency diseases RC620-627 Zahra Mardani Seyed Ali Hosseini Hassan Matinhomaee Saleh Rahmati-Ahmadabad The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2
description	Background: Exposure to hydrogen peroxide (H2O2) in addition to increase in the oxidative stress can alter mitochondrial function. The present study aimed to investigate the effect of training with coriander seed consumption on mitochondrial function and oxidative stress markers in the lung tissue of rats exposed to H2O2.Methods: Thirty-five rats were divided into 7 groups, including (i) saline healthy control, (ii) saline toxic control, (iii) coriander toxic control (500 mg/kg), (iv) coriander toxic control (1000 mg/kg), (v) coriander toxic training (500 mg/kg), (vi) coriander toxic training (1000 mg/kg), and (vii) saline toxic training groups. During eight weeks, groups 2-7 received 1 mmol/kg H2O2 for three times per week and groups 5-7 performed training three sessions per week.Results: Training and coriander significantly increased adenosine triphosphate (ATP) and decreased caspase-3, cytochrome-C, O-6- methylguanine-DNA methyltransferase (MGMT) and prealbumin (PAB) (p≤0.05). Also, interactive effects of training and coriander on increase of ATP and decrease of caspase-3, cytochrome-C, and PAB at a dose of 1000 mg/kg were higher than 500 mg/kg (p≤0.05).Conclusion: Although training and coriander alone could enhance the mitochondrial function and oxidative stress markers, training simultaneously with coriander had more favorable effects compared to each one alone.
format	article
author	Zahra Mardani Seyed Ali Hosseini Hassan Matinhomaee Saleh Rahmati-Ahmadabad
author_facet	Zahra Mardani Seyed Ali Hosseini Hassan Matinhomaee Saleh Rahmati-Ahmadabad
author_sort	Zahra Mardani
title	The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2
title_short	The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2
title_full	The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2
title_fullStr	The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2
title_full_unstemmed	The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2
title_sort	effect of aerobic training and coriander seed on oxidative stress and mitochondrial function markers in lung tissue of rats exposed to h2o2
publisher	Shiraz University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/60794bfc1d2e4774af1cedf78e7cc408
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The Effect of Aerobic Training and Coriander Seed on Oxidative Stress and Mitochondrial Function Markers in Lung Tissue of Rats Exposed to H2O2

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