Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis
Tripterygium wilfordii is a medical plant that can produce antitumor activity compound triptolide. Here, the authors assemble its genome and identify a cytochrome P450 that can catalyze oxidation of a methyl to the acid moiety of dehydroabietic acid in triptolide biosynthesis by integrating multi-om...
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Nature Portfolio
2020
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oai:doaj.org-article:607c6a54fa534ef7bf5d30b6aa59d9b02021-12-02T15:34:13ZGenome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis10.1038/s41467-020-14776-12041-1723https://doaj.org/article/607c6a54fa534ef7bf5d30b6aa59d9b02020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14776-1https://doaj.org/toc/2041-1723Tripterygium wilfordii is a medical plant that can produce antitumor activity compound triptolide. Here, the authors assemble its genome and identify a cytochrome P450 that can catalyze oxidation of a methyl to the acid moiety of dehydroabietic acid in triptolide biosynthesis by integrating multi-omics data.Lichan TuPing SuZhongren ZhangLinhui GaoJiadian WangTianyuan HuJiawei ZhouYifeng ZhangYujun ZhaoYuan LiuYadi SongYuru TongYun LuJian YangCao XuMeirong JiaReuben J. PetersLuqi HuangWei GaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Lichan Tu Ping Su Zhongren Zhang Linhui Gao Jiadian Wang Tianyuan Hu Jiawei Zhou Yifeng Zhang Yujun Zhao Yuan Liu Yadi Song Yuru Tong Yun Lu Jian Yang Cao Xu Meirong Jia Reuben J. Peters Luqi Huang Wei Gao Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis |
| description |
Tripterygium wilfordii is a medical plant that can produce antitumor activity compound triptolide. Here, the authors assemble its genome and identify a cytochrome P450 that can catalyze oxidation of a methyl to the acid moiety of dehydroabietic acid in triptolide biosynthesis by integrating multi-omics data. |
| format |
article |
| author |
Lichan Tu Ping Su Zhongren Zhang Linhui Gao Jiadian Wang Tianyuan Hu Jiawei Zhou Yifeng Zhang Yujun Zhao Yuan Liu Yadi Song Yuru Tong Yun Lu Jian Yang Cao Xu Meirong Jia Reuben J. Peters Luqi Huang Wei Gao |
| author_facet |
Lichan Tu Ping Su Zhongren Zhang Linhui Gao Jiadian Wang Tianyuan Hu Jiawei Zhou Yifeng Zhang Yujun Zhao Yuan Liu Yadi Song Yuru Tong Yun Lu Jian Yang Cao Xu Meirong Jia Reuben J. Peters Luqi Huang Wei Gao |
| author_sort |
Lichan Tu |
| title |
Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis |
| title_short |
Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis |
| title_full |
Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis |
| title_fullStr |
Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis |
| title_full_unstemmed |
Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis |
| title_sort |
genome of tripterygium wilfordii and identification of cytochrome p450 involved in triptolide biosynthesis |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/607c6a54fa534ef7bf5d30b6aa59d9b0 |
| work_keys_str_mv |
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