CUSHAW3: sensitive and accurate base-space and color-space short-read alignment with hybrid seeding.

The majority of next-generation sequencing short-reads can be properly aligned by leading aligners at high speed. However, the alignment quality can still be further improved, since usually not all reads can be correctly aligned to large genomes, such as the human genome, even for simulated data. Mo...

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Bibliographic Details
Main Authors: Yongchao Liu, Bernt Popp, Bertil Schmidt
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
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Online Access:https://doaj.org/article/607ddbc33c7f428aaefb6bdec3db870f
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