Prospective study of the evolution of blood lymphoid immune parameters during dacarbazine chemotherapy in metastatic and locally advanced melanoma patients.

Prospective study of the evolution of blood lymphoid immune parameters during dacarbazine chemotherapy in metastatic and locally advanced melanoma patients.

<h4>Background</h4>The importance of immune responses in the control of melanoma growth is well known. However, the implication of these antitumor immune responses in the efficacy of dacarbazine, a cytotoxic drug classically used in the treatment of melanoma, remains poorly understood in...

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Autores principales: Grégoire Mignot, Alice Hervieu, Pierre Vabres, Sophie Dalac, Geraldine Jeudy, Blandine Bel, Lionel Apetoh, François Ghiringhelli
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/6081e4e3111d4195adcb82f9d1b529b5
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