TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia

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TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia

Hülsemann et al. examine the role of TC10, a p21 small GTPase, in breast cancer invasion and metastasis, by regulating membrane type-1 matrix metalloproteinase (MT1- MMP) at invadopodia. The authors also develop a FRET biosensor for TC10, which is used to further investigate p190RhoGAP-dependent reg...

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Detalles Bibliográficos
Autores principales:	Maren Hülsemann, Colline Sanchez, Polina V. Verkhusha, Vera Des Marais, Serena P. H. Mao, Sara K. Donnelly, Jeffrey E. Segall, Louis Hodgson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/608534c3193740aaa779560f505d5296
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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