GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21

Childhood acute lymphoblastic leukemia is common in Latino Americans. Here, the authors conduct a genome-wide association study in a Californian cohort containing children of Latino heritage, and identify loci on 17q12 and 8q24 which may affect hematopoietic and growth-regulation pathways.

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Detalles Bibliográficos
Autores principales:	Joseph L. Wiemels, Kyle M. Walsh, Adam J. de Smith, Catherine Metayer, Semira Gonseth, Helen M. Hansen, Stephen S. Francis, Juhi Ojha, Ivan Smirnov, Lisa Barcellos, Xiaorong Xiao, Libby Morimoto, Roberta McKean-Cowdin, Rong Wang, Herbert Yu, Josephine Hoh, Andrew T. DeWan, Xiaomei Ma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/60897a19a3c545a48ff596841e051402
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spelling	oai:doaj.org-article:60897a19a3c545a48ff596841e0514022021-12-02T14:40:08ZGWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.2110.1038/s41467-017-02596-92041-1723https://doaj.org/article/60897a19a3c545a48ff596841e0514022018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02596-9https://doaj.org/toc/2041-1723Childhood acute lymphoblastic leukemia is common in Latino Americans. Here, the authors conduct a genome-wide association study in a Californian cohort containing children of Latino heritage, and identify loci on 17q12 and 8q24 which may affect hematopoietic and growth-regulation pathways.Joseph L. WiemelsKyle M. WalshAdam J. de SmithCatherine MetayerSemira GonsethHelen M. HansenStephen S. FrancisJuhi OjhaIvan SmirnovLisa BarcellosXiaorong XiaoLibby MorimotoRoberta McKean-CowdinRong WangHerbert YuJosephine HohAndrew T. DeWanXiaomei MaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joseph L. Wiemels Kyle M. Walsh Adam J. de Smith Catherine Metayer Semira Gonseth Helen M. Hansen Stephen S. Francis Juhi Ojha Ivan Smirnov Lisa Barcellos Xiaorong Xiao Libby Morimoto Roberta McKean-Cowdin Rong Wang Herbert Yu Josephine Hoh Andrew T. DeWan Xiaomei Ma GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
description	Childhood acute lymphoblastic leukemia is common in Latino Americans. Here, the authors conduct a genome-wide association study in a Californian cohort containing children of Latino heritage, and identify loci on 17q12 and 8q24 which may affect hematopoietic and growth-regulation pathways.
format	article
author	Joseph L. Wiemels Kyle M. Walsh Adam J. de Smith Catherine Metayer Semira Gonseth Helen M. Hansen Stephen S. Francis Juhi Ojha Ivan Smirnov Lisa Barcellos Xiaorong Xiao Libby Morimoto Roberta McKean-Cowdin Rong Wang Herbert Yu Josephine Hoh Andrew T. DeWan Xiaomei Ma
author_facet	Joseph L. Wiemels Kyle M. Walsh Adam J. de Smith Catherine Metayer Semira Gonseth Helen M. Hansen Stephen S. Francis Juhi Ojha Ivan Smirnov Lisa Barcellos Xiaorong Xiao Libby Morimoto Roberta McKean-Cowdin Rong Wang Herbert Yu Josephine Hoh Andrew T. DeWan Xiaomei Ma
author_sort	Joseph L. Wiemels
title	GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
title_short	GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
title_full	GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
title_fullStr	GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
title_full_unstemmed	GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
title_sort	gwas in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/60897a19a3c545a48ff596841e051402
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GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21

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