Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
Comparative epigenomics has revealed principles underlying the evolution of gene expression regulation, and the integration of epigenomic data is important for a deeper understanding of this evolution. Here the authors report the evolutionary dynamics of the epigenomic regulatory landscape in primat...
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Nature Portfolio
2021
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oai:doaj.org-article:60968dc22fd449f3aebdf1675cc35a522021-12-02T14:49:08ZEpigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures10.1038/s41467-021-23397-12041-1723https://doaj.org/article/60968dc22fd449f3aebdf1675cc35a522021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23397-1https://doaj.org/toc/2041-1723Comparative epigenomics has revealed principles underlying the evolution of gene expression regulation, and the integration of epigenomic data is important for a deeper understanding of this evolution. Here the authors report the evolutionary dynamics of the epigenomic regulatory landscape in primates and their impact in recent human evolution.Raquel García-PérezPaula Esteller-CucalaGlòria MasIrene LobónValerio Di CarloMeritxell RieraMartin KuhlwilmArcadi NavarroAntoine BlancherLuciano Di CroceJosé Luis Gómez-SkarmetaDavid JuanTomàs Marquès-BonetNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
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Science Q Raquel García-Pérez Paula Esteller-Cucala Glòria Mas Irene Lobón Valerio Di Carlo Meritxell Riera Martin Kuhlwilm Arcadi Navarro Antoine Blancher Luciano Di Croce José Luis Gómez-Skarmeta David Juan Tomàs Marquès-Bonet Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures |
description |
Comparative epigenomics has revealed principles underlying the evolution of gene expression regulation, and the integration of epigenomic data is important for a deeper understanding of this evolution. Here the authors report the evolutionary dynamics of the epigenomic regulatory landscape in primates and their impact in recent human evolution. |
format |
article |
author |
Raquel García-Pérez Paula Esteller-Cucala Glòria Mas Irene Lobón Valerio Di Carlo Meritxell Riera Martin Kuhlwilm Arcadi Navarro Antoine Blancher Luciano Di Croce José Luis Gómez-Skarmeta David Juan Tomàs Marquès-Bonet |
author_facet |
Raquel García-Pérez Paula Esteller-Cucala Glòria Mas Irene Lobón Valerio Di Carlo Meritxell Riera Martin Kuhlwilm Arcadi Navarro Antoine Blancher Luciano Di Croce José Luis Gómez-Skarmeta David Juan Tomàs Marquès-Bonet |
author_sort |
Raquel García-Pérez |
title |
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures |
title_short |
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures |
title_full |
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures |
title_fullStr |
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures |
title_full_unstemmed |
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures |
title_sort |
epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/60968dc22fd449f3aebdf1675cc35a52 |
work_keys_str_mv |
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1718389510692143104 |