Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures

Comparative epigenomics has revealed principles underlying the evolution of gene expression regulation, and the integration of epigenomic data is important for a deeper understanding of this evolution. Here the authors report the evolutionary dynamics of the epigenomic regulatory landscape in primat...

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Autores principales: Raquel García-Pérez, Paula Esteller-Cucala, Glòria Mas, Irene Lobón, Valerio Di Carlo, Meritxell Riera, Martin Kuhlwilm, Arcadi Navarro, Antoine Blancher, Luciano Di Croce, José Luis Gómez-Skarmeta, David Juan, Tomàs Marquès-Bonet
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/60968dc22fd449f3aebdf1675cc35a52
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spelling oai:doaj.org-article:60968dc22fd449f3aebdf1675cc35a522021-12-02T14:49:08ZEpigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures10.1038/s41467-021-23397-12041-1723https://doaj.org/article/60968dc22fd449f3aebdf1675cc35a522021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23397-1https://doaj.org/toc/2041-1723Comparative epigenomics has revealed principles underlying the evolution of gene expression regulation, and the integration of epigenomic data is important for a deeper understanding of this evolution. Here the authors report the evolutionary dynamics of the epigenomic regulatory landscape in primates and their impact in recent human evolution.Raquel García-PérezPaula Esteller-CucalaGlòria MasIrene LobónValerio Di CarloMeritxell RieraMartin KuhlwilmArcadi NavarroAntoine BlancherLuciano Di CroceJosé Luis Gómez-SkarmetaDavid JuanTomàs Marquès-BonetNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Raquel García-Pérez
Paula Esteller-Cucala
Glòria Mas
Irene Lobón
Valerio Di Carlo
Meritxell Riera
Martin Kuhlwilm
Arcadi Navarro
Antoine Blancher
Luciano Di Croce
José Luis Gómez-Skarmeta
David Juan
Tomàs Marquès-Bonet
Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
description Comparative epigenomics has revealed principles underlying the evolution of gene expression regulation, and the integration of epigenomic data is important for a deeper understanding of this evolution. Here the authors report the evolutionary dynamics of the epigenomic regulatory landscape in primates and their impact in recent human evolution.
format article
author Raquel García-Pérez
Paula Esteller-Cucala
Glòria Mas
Irene Lobón
Valerio Di Carlo
Meritxell Riera
Martin Kuhlwilm
Arcadi Navarro
Antoine Blancher
Luciano Di Croce
José Luis Gómez-Skarmeta
David Juan
Tomàs Marquès-Bonet
author_facet Raquel García-Pérez
Paula Esteller-Cucala
Glòria Mas
Irene Lobón
Valerio Di Carlo
Meritxell Riera
Martin Kuhlwilm
Arcadi Navarro
Antoine Blancher
Luciano Di Croce
José Luis Gómez-Skarmeta
David Juan
Tomàs Marquès-Bonet
author_sort Raquel García-Pérez
title Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
title_short Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
title_full Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
title_fullStr Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
title_full_unstemmed Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
title_sort epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/60968dc22fd449f3aebdf1675cc35a52
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