A model of tension-induced fiber growth predicts white matter organization during brain folding
Associations have been established between brain folding and white matter connectivity. Here the authors show that axon elongation, in response to mechanical stresses during cortical expansion and folding, may be sufficient to induce tissue remodeling consistent with white matter organization.
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Nature Portfolio
2021
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oai:doaj.org-article:6096f81350af43f5bd548271b27423c72021-11-21T12:34:16ZA model of tension-induced fiber growth predicts white matter organization during brain folding10.1038/s41467-021-26971-92041-1723https://doaj.org/article/6096f81350af43f5bd548271b27423c72021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26971-9https://doaj.org/toc/2041-1723Associations have been established between brain folding and white matter connectivity. Here the authors show that axon elongation, in response to mechanical stresses during cortical expansion and folding, may be sufficient to induce tissue remodeling consistent with white matter organization.Kara E. GarciaXiaojie WangChristopher D. KroenkeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Kara E. Garcia Xiaojie Wang Christopher D. Kroenke A model of tension-induced fiber growth predicts white matter organization during brain folding |
description |
Associations have been established between brain folding and white matter connectivity. Here the authors show that axon elongation, in response to mechanical stresses during cortical expansion and folding, may be sufficient to induce tissue remodeling consistent with white matter organization. |
format |
article |
author |
Kara E. Garcia Xiaojie Wang Christopher D. Kroenke |
author_facet |
Kara E. Garcia Xiaojie Wang Christopher D. Kroenke |
author_sort |
Kara E. Garcia |
title |
A model of tension-induced fiber growth predicts white matter organization during brain folding |
title_short |
A model of tension-induced fiber growth predicts white matter organization during brain folding |
title_full |
A model of tension-induced fiber growth predicts white matter organization during brain folding |
title_fullStr |
A model of tension-induced fiber growth predicts white matter organization during brain folding |
title_full_unstemmed |
A model of tension-induced fiber growth predicts white matter organization during brain folding |
title_sort |
model of tension-induced fiber growth predicts white matter organization during brain folding |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/6096f81350af43f5bd548271b27423c7 |
work_keys_str_mv |
AT karaegarcia amodeloftensioninducedfibergrowthpredictswhitematterorganizationduringbrainfolding AT xiaojiewang amodeloftensioninducedfibergrowthpredictswhitematterorganizationduringbrainfolding AT christopherdkroenke amodeloftensioninducedfibergrowthpredictswhitematterorganizationduringbrainfolding AT karaegarcia modeloftensioninducedfibergrowthpredictswhitematterorganizationduringbrainfolding AT xiaojiewang modeloftensioninducedfibergrowthpredictswhitematterorganizationduringbrainfolding AT christopherdkroenke modeloftensioninducedfibergrowthpredictswhitematterorganizationduringbrainfolding |
_version_ |
1718418886046515200 |