Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP
Pop1 and 6 are subunits of RNase P and RNase MRP, which process ribosomal and tRNAs. The authors show that when Pop1 and 6 are impaired, the telomerase subunit Est1 binds telomerase RNA at normal levels, but the binding is unstable. As a result, nuclear import of the telomerase holoenzyme is inhibit...
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Autores principales: | P. Daniela Garcia, Robert W. Leach, Gable M. Wadsworth, Krishna Choudhary, Hua Li, Sharon Aviran, Harold D. Kim, Virginia A. Zakian |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/60a84cb1852b4201965cf90b77707313 |
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