Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin

The molecular identity of the clamp that arrests the fusion machinery such that synaptic vesicles are docked and primed to release neurotransmitters remains controversial. In this study, the authors use truncation mutants of synaptotagmin (syt) 1 and animal models to demonstrate that the C2B domain...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Nicholas A. Courtney, Huan Bao, Joseph S. Briguglio, Edwin R. Chapman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/60a9c376ca40470abac94a203d8f4cc1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!