miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells

miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells

Abstract Human induced pluripotent stem (hiPS) cells are feasible materials for studying the biological mechanisms underlying human embryogenesis. In early embryogenesis, definitive endoderm and mesoderm are differentiated from their common precursor, mesendoderm. Bone morphogenetic protein (BMP) si...

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Autores principales: Jaeeun Lim, Eiko Sakai, Fuminori Sakurai, Hiroyuki Mizuguchi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/60aaa8f2f9fa4595922df2b46adea995
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