Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies

Abstract The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clinical practice and some agents have proven beneficial in treating COVID-19. Here, t...

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Autores principales:	Mu-Feng Xiang, Cheng-Tao Jin, Li-Hua Sun, Zhi-Hui Zhang, Jing-Jing Yao, Liu-Cheng Li
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Coronavirus COVID-19 SARS-CoV-2 Chinese herbal compounds Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/60addad6efac426ab1296a780ec6d258
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spelling	oai:doaj.org-article:60addad6efac426ab1296a780ec6d2582021-12-05T12:07:07ZEfficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies10.1186/s13020-021-00542-y1749-8546https://doaj.org/article/60addad6efac426ab1296a780ec6d2582021-12-01T00:00:00Zhttps://doi.org/10.1186/s13020-021-00542-yhttps://doaj.org/toc/1749-8546Abstract The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clinical practice and some agents have proven beneficial in treating COVID-19. Here, the relevant literature from basic researches to clinical application were identified and comprehensively assessed. A variety of Chinese herbal compounds have been reported to be effective in improving symptoms and outcomes in patients with COVID-19, particularly together with routine treatment strategy. The pharmacological activities were mainly attributed to the relief of clinical symptoms, inhibition of cytokine storm, and improvement of organ function. Besides, the development of novel antiviral drugs from medicinal herbs were further discussed. The updated laboratory and clinical studies provided the evidence of Chinese herbal compounds such as Lianhua Qingwen prescription, Shufeng Jiedu prescription, and Qingfei Paidu Tang for the relief of COVID-19. However, both of the randomized controlled trials and real world researches need to be done for supporting the evidence including the efficacy and safety in fighting COVID-19.Mu-Feng XiangCheng-Tao JinLi-Hua SunZhi-Hui ZhangJing-Jing YaoLiu-Cheng LiBMCarticleCoronavirusCOVID-19SARS-CoV-2Chinese herbal compoundsOther systems of medicineRZ201-999ENChinese Medicine, Vol 16, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Coronavirus COVID-19 SARS-CoV-2 Chinese herbal compounds Other systems of medicine RZ201-999
spellingShingle	Coronavirus COVID-19 SARS-CoV-2 Chinese herbal compounds Other systems of medicine RZ201-999 Mu-Feng Xiang Cheng-Tao Jin Li-Hua Sun Zhi-Hui Zhang Jing-Jing Yao Liu-Cheng Li Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
description	Abstract The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clinical practice and some agents have proven beneficial in treating COVID-19. Here, the relevant literature from basic researches to clinical application were identified and comprehensively assessed. A variety of Chinese herbal compounds have been reported to be effective in improving symptoms and outcomes in patients with COVID-19, particularly together with routine treatment strategy. The pharmacological activities were mainly attributed to the relief of clinical symptoms, inhibition of cytokine storm, and improvement of organ function. Besides, the development of novel antiviral drugs from medicinal herbs were further discussed. The updated laboratory and clinical studies provided the evidence of Chinese herbal compounds such as Lianhua Qingwen prescription, Shufeng Jiedu prescription, and Qingfei Paidu Tang for the relief of COVID-19. However, both of the randomized controlled trials and real world researches need to be done for supporting the evidence including the efficacy and safety in fighting COVID-19.
format	article
author	Mu-Feng Xiang Cheng-Tao Jin Li-Hua Sun Zhi-Hui Zhang Jing-Jing Yao Liu-Cheng Li
author_facet	Mu-Feng Xiang Cheng-Tao Jin Li-Hua Sun Zhi-Hui Zhang Jing-Jing Yao Liu-Cheng Li
author_sort	Mu-Feng Xiang
title	Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
title_short	Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
title_full	Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
title_fullStr	Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
title_full_unstemmed	Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
title_sort	efficacy and potential mechanisms of chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
publisher	BMC
publishDate	2021
url	https://doaj.org/article/60addad6efac426ab1296a780ec6d258
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Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies

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