Modeling dysbiosis of human NASH in mice: Loss of gut microbiome diversity and overgrowth of Erysipelotrichales.

Modeling dysbiosis of human NASH in mice: Loss of gut microbiome diversity and overgrowth of Erysipelotrichales.

<h4>Background & aim</h4>Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD) that is responsible for a growing fraction of cirrhosis and liver cancer cases worldwide. Changes in the gut microbiome have been implicated in NASH pathogenesi...

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Main Authors: James K Carter, Dipankar Bhattacharya, Joshua N Borgerding, M Isabel Fiel, Jeremiah J Faith, Scott L Friedman
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/60b207e17bac473783c80497954c0aa0
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