Drug Burden Index in older adults: theoretical and practical issues

Lisa Kouladjian,1 Danijela Gnjidic,1,2 Timothy F Chen,2 Arduino A Mangoni,3 Sarah N Hilmer1 1Sydney Medical School, University of Sydney, Kolling Institute of Medical Research and Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital, 2Faculty of Pharmacy, University of Syd...

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Autores principales:	Kouladjian L, Gnjidic D, Chen TF, Mangoni AA, Hilmer SN
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Drug Burden Index anticholinergic and sedative medications high-risk prescribing older adults pharmacological risk assessment tools potentially inappropriate medications Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/60b8be218d384aebb8c39ee775e78837
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spelling	oai:doaj.org-article:60b8be218d384aebb8c39ee775e788372021-12-02T07:15:38ZDrug Burden Index in older adults: theoretical and practical issues1178-1998https://doaj.org/article/60b8be218d384aebb8c39ee775e788372014-09-01T00:00:00Zhttps://www.dovepress.com/drug-burden-index-in-older-adults-theoretical-and-practical-issues-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Lisa Kouladjian,1 Danijela Gnjidic,1,2 Timothy F Chen,2 Arduino A Mangoni,3 Sarah N Hilmer1 1Sydney Medical School, University of Sydney, Kolling Institute of Medical Research and Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital, 2Faculty of Pharmacy, University of Sydney, Sydney, NSW, 3Department of Clinical Pharmacology, School of Medicine, Flinders University and Flinders Medical Centre, Bedford Park, SA, Australia Abstract: Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing. Keywords: Drug Burden Index, anticholinergics, sedative medications, high-risk prescribing, older adults, pharmacological risk assessment tools, deprescribingKouladjian LGnjidic DChen TFMangoni AAHilmer SNDove Medical PressarticleDrug Burden Indexanticholinergic and sedative medicationshigh-risk prescribingolder adultspharmacological risk assessment toolspotentially inappropriate medicationsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1503-1515 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Drug Burden Index anticholinergic and sedative medications high-risk prescribing older adults pharmacological risk assessment tools potentially inappropriate medications Geriatrics RC952-954.6
spellingShingle	Drug Burden Index anticholinergic and sedative medications high-risk prescribing older adults pharmacological risk assessment tools potentially inappropriate medications Geriatrics RC952-954.6 Kouladjian L Gnjidic D Chen TF Mangoni AA Hilmer SN Drug Burden Index in older adults: theoretical and practical issues
description	Lisa Kouladjian,1 Danijela Gnjidic,1,2 Timothy F Chen,2 Arduino A Mangoni,3 Sarah N Hilmer1 1Sydney Medical School, University of Sydney, Kolling Institute of Medical Research and Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital, 2Faculty of Pharmacy, University of Sydney, Sydney, NSW, 3Department of Clinical Pharmacology, School of Medicine, Flinders University and Flinders Medical Centre, Bedford Park, SA, Australia Abstract: Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing. Keywords: Drug Burden Index, anticholinergics, sedative medications, high-risk prescribing, older adults, pharmacological risk assessment tools, deprescribing
format	article
author	Kouladjian L Gnjidic D Chen TF Mangoni AA Hilmer SN
author_facet	Kouladjian L Gnjidic D Chen TF Mangoni AA Hilmer SN
author_sort	Kouladjian L
title	Drug Burden Index in older adults: theoretical and practical issues
title_short	Drug Burden Index in older adults: theoretical and practical issues
title_full	Drug Burden Index in older adults: theoretical and practical issues
title_fullStr	Drug Burden Index in older adults: theoretical and practical issues
title_full_unstemmed	Drug Burden Index in older adults: theoretical and practical issues
title_sort	drug burden index in older adults: theoretical and practical issues
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/60b8be218d384aebb8c39ee775e78837
work_keys_str_mv	AT kouladjianl drugburdenindexinolderadultstheoreticalandpracticalissues AT gnjidicd drugburdenindexinolderadultstheoreticalandpracticalissues AT chentf drugburdenindexinolderadultstheoreticalandpracticalissues AT mangoniaa drugburdenindexinolderadultstheoreticalandpracticalissues AT hilmersn drugburdenindexinolderadultstheoreticalandpracticalissues
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Drug Burden Index in older adults: theoretical and practical issues

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