Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
Cancer cells have been shown to be dependent upon glutamine for growth. Here, the authors show that intracellular asparagine, a glutamine-derived metabolite, is critical to cancer cell growth and can compensate glutamine deficiency by acting as an amino acid exchange factor.
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
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| Subjects: | |
| Online Access: | https://doaj.org/article/60bac93b7d0d4ccbba58a39386a3ee0d |
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