Human milk IgGs contain various combinations of different antigen-binding sites resulting in multiple variants of their bispecificity.

In the classic paradigm, immunoglobulins represent products of clonal B cell populations, each producing antibodies (Abs) recognizing a single antigen. There is a common belief that IgGs in mammalian biological fluids are monovalent molecules having stable structures and two identical antigen-bindin...

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Bibliographic Details
Main Authors: Sergey E Sedykh, Valentina N Buneva, Georgy A Nevinsky
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/60c38ab029df4fd294ca342b6e8bdd88
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