Intrinsic Toxin-Derived Peptides Destabilize and Inactivate <italic toggle="yes">Clostridium difficile</italic> TcdB
ABSTRACT Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of two large multidomain clostridial toxins, TcdA and TcdB. Both toxins coordinate the action of specific domains to bind receptors, enter...
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Autores principales: | Jason L. Larabee, Sarah J. Bland, Jonathan J. Hunt, Jimmy D. Ballard |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/60cd3efb34cd49579b838667ca9e17c7 |
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