Intrinsic Toxin-Derived Peptides Destabilize and Inactivate <italic toggle="yes">Clostridium difficile</italic> TcdB

ABSTRACT Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of two large multidomain clostridial toxins, TcdA and TcdB. Both toxins coordinate the action of specific domains to bind receptors, enter...

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Autores principales: Jason L. Larabee, Sarah J. Bland, Jonathan J. Hunt, Jimmy D. Ballard
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/60cd3efb34cd49579b838667ca9e17c7
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