The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition

Objectives. It has been shown that dysregulation of miRNAs expression contributes to the pathogenesis and progression of the diabetes and diabetes-related complications. Drosha, DGCR8, Dicer, and Ago-2 are involved in the miRNA maturation. The aim of the present study was to investigate the mRNA exp...

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Autores principales:	Soufi Farhad Ghadiri, Zonouzi Ali Akbar Poursadegh, Eftekhar Ebrahim, Kamali Kamila, Chegeni Sara Aghakhani, Zonouzi Ahmad Poursadegh
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2018
Materias:	hyperglycemia drosha dgcr8 dicer ago-2 human umbilical vein endothelial cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/60ce62fdee6a46b2a9f816e81e3a971a
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id	oai:doaj.org-article:60ce62fdee6a46b2a9f816e81e3a971a
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spelling	oai:doaj.org-article:60ce62fdee6a46b2a9f816e81e3a971a2021-12-02T19:07:36ZThe expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition1336-032910.2478/enr-2018-0014https://doaj.org/article/60ce62fdee6a46b2a9f816e81e3a971a2018-07-01T00:00:00Zhttps://doi.org/10.2478/enr-2018-0014https://doaj.org/toc/1336-0329Objectives. It has been shown that dysregulation of miRNAs expression contributes to the pathogenesis and progression of the diabetes and diabetes-related complications. Drosha, DGCR8, Dicer, and Ago-2 are involved in the miRNA maturation. The aim of the present study was to investigate the mRNA expression levels of these genes in the human umbilical vein endothelial cells (HUVECs) under hyperglycemic condition.Soufi Farhad GhadiriZonouzi Ali Akbar PoursadeghEftekhar EbrahimKamali KamilaChegeni Sara AghakhaniZonouzi Ahmad PoursadeghSciendoarticlehyperglycemiadroshadgcr8dicerago-2human umbilical vein endothelial cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 52, Iss 3, Pp 123-127 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	hyperglycemia drosha dgcr8 dicer ago-2 human umbilical vein endothelial cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	hyperglycemia drosha dgcr8 dicer ago-2 human umbilical vein endothelial cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 Soufi Farhad Ghadiri Zonouzi Ali Akbar Poursadegh Eftekhar Ebrahim Kamali Kamila Chegeni Sara Aghakhani Zonouzi Ahmad Poursadegh The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
description	Objectives. It has been shown that dysregulation of miRNAs expression contributes to the pathogenesis and progression of the diabetes and diabetes-related complications. Drosha, DGCR8, Dicer, and Ago-2 are involved in the miRNA maturation. The aim of the present study was to investigate the mRNA expression levels of these genes in the human umbilical vein endothelial cells (HUVECs) under hyperglycemic condition.
format	article
author	Soufi Farhad Ghadiri Zonouzi Ali Akbar Poursadegh Eftekhar Ebrahim Kamali Kamila Chegeni Sara Aghakhani Zonouzi Ahmad Poursadegh
author_facet	Soufi Farhad Ghadiri Zonouzi Ali Akbar Poursadegh Eftekhar Ebrahim Kamali Kamila Chegeni Sara Aghakhani Zonouzi Ahmad Poursadegh
author_sort	Soufi Farhad Ghadiri
title	The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
title_short	The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
title_full	The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
title_fullStr	The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
title_full_unstemmed	The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
title_sort	expression of drosha, dgcr8, dicer and ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition
publisher	Sciendo
publishDate	2018
url	https://doaj.org/article/60ce62fdee6a46b2a9f816e81e3a971a
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The expression of Drosha, DGCR8, Dicer and Ago-2 genes are upregulated in human umbilical vein endothelial cells under hyperglycemic condition

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