Upregulation of 5′-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor
Abstract Tumor cells require nominal increases in protein synthesis in order to maintain high proliferation rates. As such, tumor cells must acquire enhanced ribosome production. How the numerous mutations in tumor cells ultimately achieve this aberrant production is largely unknown. The gene encodi...
Guardado en:
Autores principales: | Kyle A. Cottrell, Ryan C. Chiou, Jason D. Weber |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/60e397c48e944433a97436aa66b949cd |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
ArfB can displace mRNA to rescue stalled ribosomes
por: Christine E. Carbone, et al.
Publicado: (2020) -
Translation of human Δ133p53 mRNA and its targeting by antisense oligonucleotides complementary to the 5'-terminal region of this mRNA.
por: Paulina Żydowicz-Machtel, et al.
Publicado: (2021) -
Variants of the 5′-terminal region of p53 mRNA influence the ribosomal scanning and translation efficiency
por: Paulina Zydowicz-Machtel, et al.
Publicado: (2018) -
The SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation.
por: Véronique Joliot, et al.
Publicado: (2014) -
Editorial: RNA-Protein Interactions in mRNA Translation and Decay
por: Purusharth I. Rajyaguru, et al.
Publicado: (2021)