MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
Abstract Many immune suppressive mechanisms utilized by triple negative breast cancer (TNBC) are regulated by oncogenic epithelial-to-mesenchymal transition (EMT). How TNBC EMT impacts innate immune cells is not fully understood. To determine how TNBC suppresses antitumor macrophages, we used microR...
Guardado en:
Autores principales: | Michelle M. Williams, Jessica L. Christenson, Kathleen I. O’Neill, Sabrina A. Hafeez, Claire L. Ihle, Nicole S. Spoelstra, Jill E. Slansky, Jennifer K. Richer |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/60e89acc1885465fafd6cd0d4bea2bf5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Reversing an Oncogenic Epithelial-to-Mesenchymal Transition Program in Breast Cancer Reveals Actionable Immune Suppressive Pathways
por: Michelle M. Williams, et al.
Publicado: (2021) -
Secreted indicators of androgen receptor activity in breast cancer pre-clinical models
por: Toru Hanamura, et al.
Publicado: (2021) -
Macrophage polarization in sarcoidosis
por: I. E. Malysheva, et al.
Publicado: (2021) -
Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals
por: Tetsuya Kimura, et al.
Publicado: (2016) -
Erratum: Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals
por: Tetsuya Kimura, et al.
Publicado: (2017)