Model-driven generation of artificial yeast promoters

A small set of promoters is used for most genetic construct design in S. cerevisiae. Here, the authors develop a predictive model of promoter activity trained on a data set of over one million sequences and use it to design large sets of high-activity promoters.

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Detalles Bibliográficos
Autores principales: Benjamin J. Kotopka, Christina D. Smolke
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/60f4d5679ca14b2e8e6f8ec1bb4c67b7
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