Model-driven generation of artificial yeast promoters

A small set of promoters is used for most genetic construct design in S. cerevisiae. Here, the authors develop a predictive model of promoter activity trained on a data set of over one million sequences and use it to design large sets of high-activity promoters.

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Auteurs principaux: Benjamin J. Kotopka, Christina D. Smolke
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Q
Accès en ligne:https://doaj.org/article/60f4d5679ca14b2e8e6f8ec1bb4c67b7
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