Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions

Cell membrane interface is mostly studied using synthetic bilayers and reconstituted cell membranes. Here the authors present a new cell fixation method in which the cytoskeleton is replaced by a synthetic hydrogel polymer network assembled inside the cell, thereby preserving the fluid membrane prop...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jung-Chen Lin, Chen-Ying Chien, Chi-Long Lin, Bing-Yu Yao, Yuan-I Chen, Yu-Han Liu, Zih-Syun Fang, Jui-Yi Chen, Wei-ya Chen, No-No Lee, Hui-Wen Chen, Che-Ming J. Hu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/60f70ab26b30453c9a34acb65a4bb0ab
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:60f70ab26b30453c9a34acb65a4bb0ab
record_format	dspace
spelling	oai:doaj.org-article:60f70ab26b30453c9a34acb65a4bb0ab2021-12-02T15:35:16ZIntracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions10.1038/s41467-019-09049-52041-1723https://doaj.org/article/60f70ab26b30453c9a34acb65a4bb0ab2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09049-5https://doaj.org/toc/2041-1723Cell membrane interface is mostly studied using synthetic bilayers and reconstituted cell membranes. Here the authors present a new cell fixation method in which the cytoskeleton is replaced by a synthetic hydrogel polymer network assembled inside the cell, thereby preserving the fluid membrane properties after cell death.Jung-Chen LinChen-Ying ChienChi-Long LinBing-Yu YaoYuan-I ChenYu-Han LiuZih-Syun FangJui-Yi ChenWei-ya ChenNo-No LeeHui-Wen ChenChe-Ming J. HuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jung-Chen Lin Chen-Ying Chien Chi-Long Lin Bing-Yu Yao Yuan-I Chen Yu-Han Liu Zih-Syun Fang Jui-Yi Chen Wei-ya Chen No-No Lee Hui-Wen Chen Che-Ming J. Hu Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions
description	Cell membrane interface is mostly studied using synthetic bilayers and reconstituted cell membranes. Here the authors present a new cell fixation method in which the cytoskeleton is replaced by a synthetic hydrogel polymer network assembled inside the cell, thereby preserving the fluid membrane properties after cell death.
format	article
author	Jung-Chen Lin Chen-Ying Chien Chi-Long Lin Bing-Yu Yao Yuan-I Chen Yu-Han Liu Zih-Syun Fang Jui-Yi Chen Wei-ya Chen No-No Lee Hui-Wen Chen Che-Ming J. Hu
author_facet	Jung-Chen Lin Chen-Ying Chien Chi-Long Lin Bing-Yu Yao Yuan-I Chen Yu-Han Liu Zih-Syun Fang Jui-Yi Chen Wei-ya Chen No-No Lee Hui-Wen Chen Che-Ming J. Hu
author_sort	Jung-Chen Lin
title	Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions
title_short	Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions
title_full	Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions
title_fullStr	Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions
title_full_unstemmed	Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions
title_sort	intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/60f70ab26b30453c9a34acb65a4bb0ab
work_keys_str_mv	AT jungchenlin intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT chenyingchien intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT chilonglin intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT bingyuyao intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT yuanichen intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT yuhanliu intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT zihsyunfang intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT juiyichen intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT weiyachen intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT nonolee intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT huiwenchen intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions AT chemingjhu intracellularhydrogelationpreservesfluidandfunctionalcellmembraneinterfacesforbiologicalinteractions
_version_	1718386599483408384

Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions

Ejemplares similares