Regioisomers Salviprolin A and B, Unprecedented Rosmarinic Acid Conjugated Dinorditerpenoids from <i>Salvia przewalskii</i> Maxim
<i>Salvia przewalskii</i> Maxim is a perennial plant from the genus <i>Salvia</i> (family Lamiaceae). The roots of <i>S. przewalskii</i> were long used as a traditional herb to treat blood circulation related illnesses in China. As part of our continuing interest...
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| Autores principales: | , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/60f8794d17764237bc613a49d2c67b02 |
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| Sumario: | <i>Salvia przewalskii</i> Maxim is a perennial plant from the genus <i>Salvia</i> (family Lamiaceae). The roots of <i>S. przewalskii</i> were long used as a traditional herb to treat blood circulation related illnesses in China. As part of our continuing interest in polycyclic natural products from medicinal plants, two unprecedented adducts comprised of a <i>dinor</i>-diterpenoid and a 9′-<i>nor</i>-rosmarinic acid derivative, linked by a 1,4-benzodioxane motif (<b>1</b> and <b>2</b>), were isolated from the roots of <i>S. przewalskii</i>. Their structures were established by extensive spectroscopic approaches including 1D, 2D NMR, and HRFABMS. Their cytotoxic activities against five human tumor cell lines were evaluated. |
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